Involvement of PTEN/Akt signaling in capsular invasive carcinomas developed in a rat two-stage thyroid carcinogenesis model after promotion with sulfadimethoxine. (Q53297775)

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scientific article published on 26 June 2010

Language	Label	Description	Also known as
English	Involvement of PTEN/Akt signaling in capsular invasive carcinomas developed in a rat two-stage thyroid carcinogenesis model after promotion with sulfadimethoxine.	scientific article published on 26 June 2010

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6 February 2020

Involvement of PTEN/Akt signaling in capsular invasive carcinomas developed in a rat two-stage thyroid carcinogenesis model after promotion with sulfadimethoxine (English)

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6 February 2020

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Kunitoshi Mitsumori

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6 February 2020

Makoto Shibutani

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Makoto Shibutani

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6 February 2020

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Sayaka Kemmochi

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6 February 2020

Hitoshi Fujimoto

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Gye-Hyeong Woo

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Kaoru Inoue

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Miwa Takahashi

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Masao Hirose

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Akiyoshi Nishikawa

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26 June 2010

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6 February 2020

Journal of Cancer Research and Clinical Oncology

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6 February 2020

137

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6 February 2020

https://scigraph.springernature.com/pub.10.1007/s00432-010-0931-7

0 references

Involvement of glycogen synthase kinase-3beta signaling and aberrant nucleocytoplasmic localization of retinoblastoma protein in tumor promotion in a rat two-stage thyroid carcinogenesis model.

1 reference

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mTOR: a protein kinase switching between life and death

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PTEN, more than the AKT pathway

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Mammary epithelial-mesenchymal interaction regulates fibronectin alternative splicing via phosphatidylinositol 3-kinase.

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression

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Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer.

1 reference

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PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer

1 reference

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Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

1 reference

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21 January 2018

Sequential analysis of development of invasive thyroid follicular cell carcinomas in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation

1 reference

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21 January 2018

Development of invasive follicular cell carcinomas in a rat thyroid carcinogenesis model: biological impact of capsular inflammation and reduced cyclooxygenase-2 expression.

1 reference

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21 January 2018

Depression of T cell-mediated immunity reduces sulfadimethoxine-induced capsular inflammation and inhibits associated development of invasive thyroid follicular cell carcinomas in rats.

1 reference

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21 January 2018

Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cells

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Increased incidence of well-differentiated thyroid cancer associated with Hashimoto thyroiditis and the role of the PI3k/Akt pathway.

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Methacarn fixation--effects of tissue processing and storage conditions on detection of mRNAs and proteins in paraffin-embedded tissues

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Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression

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Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

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21 January 2018

Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice

1 reference

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21 January 2018

Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin.

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21 January 2018

Akt signaling and cancer: surviving but not moving on.

1 reference

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21 January 2018

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

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21 January 2018

Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology

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21 January 2018

A knotty turnabout?: Akt1 as a metastasis suppressor

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21 January 2018

Targeting Akt in cancer therapy

1 reference

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12 December 2020

based on heuristic

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Phosphatidylinositol-3 kinase dependent pathways: the role in control of cell growth, survival, and malignant transformation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20582435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20582435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression and overactivation of Akt in thyroid carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20582435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of PTEN (phosphatase and tensin homologue deleted on chromosome ten) protein is enhanced in human fibromyomatous uteri

1 reference

https://pubmed.ncbi.nlm.nih.gov/20582435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00432-010-0931-7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582435%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582435%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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