Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor. (Q34333813)

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English	Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.	scientific article

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20 December 2019

Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor (English)

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20 December 2019

Jeffrey C. Horowitz

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20 December 2019

Venkateshwar G Keshamouni

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20 December 2019

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Daniel Y Lee

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20 December 2019

Meghna Waghray

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20 December 2019

Peedikayil E Thomas

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20 December 2019

Hengmin Zhang

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20 December 2019

Zongbin Cui

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20 December 2019

Victor J Thannickal

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23 October 2003

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20 December 2019

Journal of Biological Chemistry

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20 December 2019

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20 December 2019

1359-1367

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20 December 2019

2

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20 December 2019

Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis.

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6 July 2018

Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.

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6 July 2018

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

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6 July 2018

Epithelial to mesenchymal transition in Madin-Darby canine kidney cells is accompanied by down-regulation of Smad3 expression, leading to resistance to transforming growth factor-beta-induced growth arrest.

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6 July 2018

TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1

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6 July 2018

PKB binding proteins. Getting in on the Akt.

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6 July 2018

TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses

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Myofibroblasts and mechano-regulation of connective tissue remodelling

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Inhibitory mechanisms of tea polyphenols on the ultraviolet B-activated phosphatidylinositol 3-kinase-dependent pathway

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How cells read TGF-beta signals

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TGFbeta signaling in growth control, cancer, and heritable disorders

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Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

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6 July 2018

Transforming growth factor-beta 1-induced activation of the ERK pathway/activator protein-1 in human lung fibroblasts requires the autocrine induction of basic fibroblast growth factor

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6 July 2018

Role of transforming growth factor beta in human disease

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6 July 2018

The acute respiratory distress syndrome

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6 July 2018

Cellular survival: a play in three Akts

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6 July 2018

Transforming growth factor beta induces caspase 3-independent cleavage of alphaII-spectrin (alpha-fodrin) coincident with apoptosis

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6 July 2018

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

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XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

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6 July 2018

Upregulated expression of fibroblast growth factor (FGF) receptors by transforming growth factor-beta1 (TGF-beta1) mediates enhanced mitogenic responses to FGFs in cultured human lung fibroblasts

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6 July 2018

Role of transforming growth factor-beta in tissue injury and repair

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6 July 2018

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

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6 July 2018

Activation of an H2O2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1.

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Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

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Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

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Transforming growth factor beta in tissue fibrosis

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Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.

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Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta

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Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity

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Meeting report: signaling schemes for TGF-beta

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12 December 2020

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Involvement of growth factor receptors in the mammalian UVC response

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12 December 2020

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The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes

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Tyrosine phosphorylation regulates H2O2 production in lung fibroblasts stimulated by transforming growth factor beta1

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Suppression of transforming growth factor-beta-induced apoptosis through a phosphatidylinositol 3-kinase/Akt-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/14576166

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Release of mechanical tension triggers apoptosis of human fibroblasts in a model of regressing granulation tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/14576166

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Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/14576166

12 December 2020

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Inhibition of myofibroblast apoptosis by transforming growth factor beta(1)

1 reference

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Role of apoptosis and transforming growth factor beta1 in fibroblast selection and activation in systemic sclerosis

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Identifiers

10.1074/JBC.M306248200

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20 December 2019

1 reference

Europe PubMed Central

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20 December 2019

1 reference

Europe PubMed Central

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20 December 2019

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