Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction. (Q53293095)

13 May 2018

title

Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction. (English)

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13 May 2018

author name string

Subhas C Biswas

series ordinal

1

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13 May 2018

Jean Buteau

series ordinal

2

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13 May 2018

Lloyd A Greene

series ordinal

3

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13 May 2018

publication date

20 March 2008

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13 May 2018

published in

Neurochemical Research

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13 May 2018

volume

33

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13 May 2018

issue

9

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13 May 2018

page(s)

1845-1851

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13 May 2018

https://scigraph.springernature.com/pub.10.1007/s11064-008-9646-4

exact match

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cites work

Neuronal structure is altered by amyloid plaques

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Nerve growth factor and diabetic neuropathy

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Cell cycle molecules define a pathway required for neuron death in development and disease

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Cellular localization of proglucagon/glucagon-like peptide I messenger RNAs in rat brain

21 January 2018

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12 December 2020

Glucagon-like peptide 1 and its derivatives in the treatment of diabetes.

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12 December 2020

Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

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cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells

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12 December 2020

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

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12 December 2020

Central administration of glucagon-like peptide-1 activates hypothalamic neuroendocrine neurons in the rat.

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12 December 2020

Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.

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12 December 2020

Glucagon-like peptide-1 prevents beta cell glucolipotoxicity

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12 December 2020

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

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12 December 2020

Identification of specific binding sites for glucagon-like peptide-1 on the posterior lobe of the rat pituitary

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12 December 2020

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

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12 December 2020

Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells

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12 December 2020

Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4.

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New Therapeutic Strategies and Drug Candidates for Neurodegenerative Diseases: p53 and TNF- Inhibitors, and GLP-1 Receptor Agonists

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BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

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12 December 2020

Distribution of glucagonlike peptide I (GLP-I), glucagon, and glicentin in the rat brain: an immunocytochemical study

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12 December 2020

Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.

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12 December 2020

Characterization of human and rat glucagon-like peptide-1 receptors in the neurointermediate lobe: lack of coupling to either stimulation or inhibition of adenylyl cyclase

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12 December 2020

Integrative mitogenic role of protein kinase B/Akt in beta-cells.

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12 December 2020

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

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12 December 2020

Glucagon-like peptide-1 receptor is involved in learning and neuroprotection

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12 December 2020

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

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12 December 2020

A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells

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12 December 2020

Neurotrophin signaling via Trks and p75.

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12 December 2020

Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons.

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12 December 2020

Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells

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12 December 2020

Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy

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12 December 2020

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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Nerve growth factor signaling, neuroprotection, and neural repair

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The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

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Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.

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12 December 2020

Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells

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12 December 2020

Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 5'-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway

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12 December 2020

c-Jun and the transcriptional control of neuronal apoptosis

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12 December 2020

Life in the balance: how BH3-only proteins induce apoptosis.

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12 December 2020

Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation

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12 December 2020

Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass.

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12 December 2020

Glucagon-like peptide-1 receptor (GLP1-R) mRNA in the rat hypothalamus.

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12 December 2020

Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats.

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12 December 2020

Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system.

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12 December 2020

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

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12 December 2020

Nerve growth factor in treatment and pathogenesis of Alzheimer's disease.

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12 December 2020

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis

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12 December 2020

Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor

1 reference

12 December 2020

10.1007/S11064-008-9646-4

Identifiers

DOI

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13 May 2018

PubMed ID

18351462

1 reference

13 May 2018