Bexarotene Promotes Cholesterol Efflux and Restricts Apical-to-Basolateral Transport of Amyloid-β Peptides in an In Vitro Model of the Human Blood-Brain Barrier. (Q52148894)

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scientific article published on 11 September 2015

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English	Bexarotene Promotes Cholesterol Efflux and Restricts Apical-to-Basolateral Transport of Amyloid-β Peptides in an In Vitro Model of the Human Blood-Brain Barrier.	scientific article published on 11 September 2015

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scholarly article

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

Bexarotene Promotes Cholesterol Efflux and Restricts Apical-to-Basolateral Transport of Amyloid-β Peptides in an In Vitro Model of the Human Blood-Brain Barrier. (English)

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

blood–brain barrier

1 reference

based on heuristic

inferred from title

Fabien Gosselet

8

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

Laurence Fenart

object named as

Laurence Fenart

7

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author name string

Mélanie Kuntz

1

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

Pietra Candela

2

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

Julien Saint-Pol

3

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

Yordenca Lamartinière

4

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

Marie-Christine Boucau

5

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

Emmanuel Sevin

6

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

publication date

11 September 2015

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Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

Journal of Alzheimer's Disease

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Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

48

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Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

3

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Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

849-862

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Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

copyright license

Creative Commons Attribution-NonCommercial 4.0 International

1 October 2015

1 reference

April 2022 Public Data File from Crossref

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0 references

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1 reference

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1 reference

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Identifiers

10.3233/JAD-150469

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

1 reference

Europe PubMed Central

23 April 2018

http://europepmc.org/abstract/MED/26402114

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