Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease (Q46738145)

24 December 2017

title

Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease (English)

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24 December 2017

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7

David M Holtzman

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24 December 2017

Suzanne E Wahrle

1

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24 December 2017

Hong Jiang

2

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24 December 2017

Maia Parsadanian

3

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24 December 2017

Richard E Hartman

4

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24 December 2017

Kelly R Bales

5

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24 December 2017

Steven M Paul

6

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24 December 2017

language of work or name

English

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publication date

5 October 2005

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

280

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24 December 2017

page(s)

43236-43242

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24 December 2017

issue

52

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24 December 2017

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Biology of A beta amyloid in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Structure, function and regulation of the ABC1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Regulation and Mechanisms of ATP-Binding Cassette Transporter A1-Mediated Cellular Cholesterol Efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Metabolism of High-Density Lipoprotein Apolipoproteins in Tangier Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Cholesterol and the biology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Expression of Liver X Receptor Target Genes Decreases Cellular Amyloid β Peptide Secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

In vivo effects of ApoE and clusterin on amyloid-beta metabolism and neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

21 January 2018

Identifiers

DOI

10.1074/JBC.M508780200

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24 December 2017

PubMed ID

16207708

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24 December 2017