Chromosomal translocation master genes, mouse models and experimental therapeutics. (Q52128463)

22 April 2018

title

Chromosomal translocation master genes, mouse models and experimental therapeutics. (English)

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22 April 2018

author name string

Rabbitts TH

series ordinal

1

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22 April 2018

language of work or name

English

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publication date

1 September 2001

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22 April 2018

published in

Oncogene

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22 April 2018

volume

20

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22 April 2018

issue

40

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22 April 2018

page(s)

5763-5777

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22 April 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204597

exact match

0 references

cites work

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Oncogenic conversion of transcription factors by chromosomal translocations

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Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

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An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

21 January 2018

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Chromosomal location of the genes for human immunoglobulin heavy chains

21 January 2018

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Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

21 January 2018

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Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

21 January 2018

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The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

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Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

21 January 2018

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Natural and engineered disorders of lymphocyte development

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The oncogenic T cell LIM-protein Lmo2 forms part of a DNA-binding complex specifically in immature T cells

21 January 2018

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

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Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

21 January 2018

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DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations.

21 January 2018

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Three-dimensional structure of beta-galactosidase from E. coli

21 January 2018

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HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

21 January 2018

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The role of gene dosage and genetic transpositions in carcinogenesis

21 January 2018

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Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases

21 January 2018

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Synthetic activation of caspases: artificial death switches

21 January 2018

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Localization of human immunoglobulin kappa light chain variable region genes to the short arm of chromosome 2 by in situ hybridization.

21 January 2018

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Expression of an antibody fragment at high levels in the bacterial cytoplasm.

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The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein

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The nineteenth Colworth Medal Lecture. The human immunoglobulin genes.

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Translocations, master genes, and differences between the origins of acute and chronic leukemias

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Chromosomal translocations in human cancer.

21 January 2018

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LMO T-cell translocation oncogenes typify genes activated by chromosomal translocations that alter transcription and developmental processes.

21 January 2018

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Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.

21 January 2018

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Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

21 January 2018

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Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma.

21 January 2018

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TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

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Transcriptional activation by TAL1 and FUS-CHOP proteins expressed in acute malignancies as a result of chromosomal abnormalities.

21 January 2018

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The LIM domain is a modular protein-binding interface

21 January 2018

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A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

21 January 2018

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Masked antisense: a molecular configuration for discriminating similar RNA targets

21 January 2018

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Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

21 January 2018

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Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack

21 January 2018

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Intracellular antibody-caspase-mediated cell killing: an approach for application in cancer therapy.

21 January 2018

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The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells

21 January 2018

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Cre-mediated site-specific translocation between nonhomologous mouse chromosomes

21 January 2018

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Selection of antibodies for intracellular function using a two-hybrid in vivo system

21 January 2018

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The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

21 January 2018

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Antisense technology and prospects for therapy of viral infections and cancer

21 January 2018

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The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

21 January 2018

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Making antibodies by phage display technology

21 January 2018

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The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice

21 January 2018

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The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis.

21 January 2018

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Immunoglobulin heavy chain genes in humans are located on chromosome 14

21 January 2018

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A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

21 January 2018

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Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

21 January 2018

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7 January 2021

The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line

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7 January 2021

Cytogenetic studies on African Burkitt's lymphoma cell lines: t(8;14), t(2;8) and t(8;22) translocations

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Specific chromosome aberration in human renal cell carcinoma

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The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204597

1 reference

22 April 2018

Dimensions Publication ID

0 references

1 reference

22 April 2018