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The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line (Q74083363)

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scientific article published on 01 July 2000

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English	The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line	scientific article published on 01 July 2000

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8 November 2019

The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line (English)

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8 November 2019

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Bemark M

1

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8 November 2019

Neuberger MS

2

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8 November 2019

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1 July 2000

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8 November 2019

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8 November 2019

19

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8 November 2019

30

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8 November 2019

3404-3410

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8 November 2019

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1 reference

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Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

1 reference

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Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

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Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma

1 reference

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The c-myc gene encodes superimposed RNA polymerase II and III promoters

1 reference

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Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

1 reference

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Mismatch Repair Deficiency Interferes with the Accumulation of Mutations in Chronically Stimulated B Cells and Not with the Hypermutation Process

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Somatic hypermutation in the heavy chain locus correlates with transcription

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Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

1 reference

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Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers.

1 reference

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c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

1 reference

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Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene.

1 reference

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c-mycHypermutation in Burkitt's Lymphoma

1 reference

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Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes

1 reference

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Intrinsic sites of transcription termination and pausing in the c-myc gene

1 reference

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Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

1 reference

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Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

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Somatic mutation and transcriptional deregulation of myc in endemic Burkitt's lymphoma disease: heptamer-nonamer recognition mistakes?

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Persistence of immunoglobulin heavy chain/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men

1 reference

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Reciprocal chromosome translocation between c-myc and immunoglobulin gamma 2b genes

1 reference

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BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

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7 January 2021

based on heuristic

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Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

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7 January 2021

based on heuristic

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A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus

1 reference

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7 January 2021

based on heuristic

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Transcription enhancer identified near the human C mu immunoglobulin heavy chain gene is unavailable to the translocated c-myc gene in a Burkitt lymphoma.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.

1 reference

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7 January 2021

based on heuristic

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Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The 5' hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription.

1 reference

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Hot Spot Focusing of Somatic Hypermutation in MSH2-Deficient Mice Suggests Two Stages of Mutational Targeting

1 reference

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based on heuristic

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TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

1 reference

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Mutation of BCL-6 Gene in Normal B Cells by the Process of Somatic Hypermutation of Ig Genes

1 reference

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MYC oncogene involved in a t(8;22) chromosome translocation is not altered in its putative regulatory regions

1 reference

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based on heuristic

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The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles

1 reference

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Allele-specific activation of the c-myc gene in an atypical Burkitt's lymphoma carrying the t(2;8) chromosomal translocation 250 kb downstream from c-myc

1 reference

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Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

1 reference

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Activation and somatic mutation of the translocated c-myc gene in burkitt lymphoma cells

1 reference

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Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches

1 reference

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The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

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Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)

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Somatic hypermutation of immunoglobulin genes

1 reference

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Somatic Hypermutation Introduces Insertions and Deletions into Immunoglobulin V Genes

1 reference

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Activation of a translocated c-myc gene: role of structural alterations in the upstream region

1 reference

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based on heuristic

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Targeting of non-Ig sequences in place of the V segment by somatic hypermutation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A point mutation in the c-myc locus of a Burkitt lymphoma abolishes binding of a nuclear protein

1 reference

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based on heuristic

inferred from DOI database lookup

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