ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain. (Q48596350)

13 February 2018

title

ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain. (English)

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13 February 2018

main subject

Apolipoprotein A1

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positive regulation of phospholipid efflux

GOA release 2020-03-11

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ATP-binding cassette, sub-family A (ABC1), member 7

GOA release 2020-03-11

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GOA release 2020-03-11

author

Glenda Halliday

4

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13 February 2018

George Paxinos

3

object named as

George Paxinos

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author name string

YuHong Fu

1

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13 February 2018

Jen-Hsiang T Hsiao

2

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13 February 2018

Woojin Scott Kim

5

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13 February 2018

publication date

25 July 2016

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13 February 2018

Journal of Alzheimer's Disease

published in

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13 February 2018

volume

54

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13 February 2018

issue

2

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13 February 2018

page(s)

569-584

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13 February 2018

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

cites work

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7)

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

ABCA7 expression is regulated by cellular cholesterol through the SREBP2 pathway and associated with phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Chronic exposure of human neurons to quinolinic acid results in neuronal changes consistent with AIDS dementia complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway: 1-phenyl-2-decanoylamino-3-morpholino-1-propanol is a novel cholesterol efflux accelerator

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Hematopoietic CC-chemokine receptor 2 (CCR2) competent cells are protective for the cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Scavenger receptor class B type I (SR-BI) regulates perivascular macrophages and modifies amyloid pathology in an Alzheimer mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Association of genetic variants of ABCA1 with Alzheimer's disease risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

ApoE promotes the proteolytic degradation of Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Involvement of mitogen-activated protein kinases in class B scavenger receptor type I-induced phagocytosis of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Thrombospondin stimulates focal adhesion disassembly through Gi- and phosphoinositide 3-kinase-dependent ERK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Actin reorganization and morphological changes in human neutrophils stimulated by TNF, GM-CSF, and G-CSF: the role of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Regulation of cell motility by mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

Increased cholesterol in Abeta-positive nerve terminals from Alzheimer's disease cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160456

21 January 2018

Identifiers

DOI

10.3233/JAD-160456

1 reference

13 February 2018

PubMed ID

27472885

1 reference

13 February 2018