The role of Runx2 in facilitating autophagy in metastatic breast cancer cells. (Q48359215)

http://europepmc.org/abstract/MED/28345763

11 February 2018

title

The role of Runx2 in facilitating autophagy in metastatic breast cancer cells. (English)

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http://europepmc.org/abstract/MED/28345763

11 February 2018

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metastatic breast cancer

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Manish Tandon

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28345763%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Ahmad H Othman

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28345763%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Vivek Ashok

series ordinal

3

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3 June 2020

publication date

27 March 2017

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http://europepmc.org/abstract/MED/28345763

11 February 2018

published in

Journal of Cellular Physiology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28345763%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

233

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3 June 2020

issue

1

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3 June 2020

page(s)

559-571

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Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

3 June 2020

cites work

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21 January 2018

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α-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration

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RUNX2 is overexpressed in melanoma cells and mediates their migration and invasion

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RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression

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The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer

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Critical roles for nitric oxide and ERK in the completion of prosurvival autophagy in 4OHTAM-treated estrogen receptor-positive breast cancer cells

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p53-regulated autophagy is controlled by glycolysis and determines cell fate

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Expression and function of Cbfa-1/Runx2 in thyroid papillary carcinoma cells

21 January 2018

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The machinery of macroautophagy

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RUNX2 in mammary gland development and breast cancer.

21 January 2018

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Role of Runx2 phosphorylation in prostate cancer and association with metastatic disease

21 January 2018

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Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation

21 January 2018

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An autophagic switch in the response of tumor cells to radiation and chemotherapy

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HDAC6 is a microtubule-associated deacetylase

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21 January 2018

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The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes

21 January 2018

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Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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A multigenic program mediating breast cancer metastasis to bone

21 January 2018

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Autophagy and metastasis: another double-edged sword

21 January 2018

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AMPK connects energy stress to PIK3C3/VPS34 regulation

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

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21 January 2018

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Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

21 January 2018

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

21 January 2018

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Integrity of actin fibers and microtubules influences metastatic tumor cell adhesion.

21 January 2018

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Breast cancer metastasis to bone: mechanisms of osteolysis and implications for therapy

21 January 2018

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Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens

21 January 2018

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Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate α-tubulin acetyltransferase-1 (αTAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress

21 January 2018

1 reference

Autophagy and microtubules - new story, old players.

21 January 2018

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The Role of RUNX2 in Osteosarcoma Oncogenesis

21 January 2018

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Autophagy proteins regulate ERK phosphorylation

21 January 2018

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Metastatic breast tumors express increased tau, which promotes microtentacle formation and the reattachment of detached breast tumor cells

21 January 2018

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The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

21 January 2018

1 reference

How to interpret LC3 immunoblotting

21 January 2018

1 reference

Methods in mammalian autophagy research

21 January 2018

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Multiple roles of the cytoskeleton in autophagy

21 January 2018

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Novel insights into how autophagy regulates tumor cell motility

21 January 2018

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Autophagy in cancer metastasis

21 January 2018

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Runx2 in human breast carcinoma: its potential roles in cancer progression.

21 January 2018

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Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer

21 January 2018

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Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2.

21 January 2018

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Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression

21 January 2018

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Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.

21 January 2018

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Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

21 January 2018

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Microenvironmental regulation of tumor progression and metastasis

21 January 2018

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21 January 2018

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Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3

21 January 2018

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A role for Runx2 in normal mammary gland and breast cancer bone metastasis

21 January 2018

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21 January 2018

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PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

21 January 2018

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Role of Runx2 in IGF-1Rβ/Akt- and AMPK/Erk-dependent growth, survival and sensitivity towards metformin in breast cancer bone metastasis.

21 January 2018

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Role of Runx2 in crosstalk between Mek/Erk and PI3K/Akt signaling in MCF-10A cells

21 January 2018

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Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells

21 January 2018

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Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells

21 January 2018

1 reference

Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions

21 January 2018

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PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update

21 January 2018

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Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

21 January 2018

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The role for autophagy in cancer

21 January 2018

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Suppressed autophagy flux in skeletal muscle of an amyotrophic lateral sclerosis mouse model during disease progression

21 January 2018

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Acetylated microtubules are required for fusion of autophagosomes with lysosomes

21 January 2018

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Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally

21 January 2018

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Chapter 10 Monitoring Autophagy by Electron Microscopy in Mammalian Cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.25916

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28345763%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

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