Role of Runx2 in crosstalk between Mek/Erk and PI3K/Akt signaling in MCF-10A cells (Q38963788)

8 September 2017

Role of Runx2 in crosstalk between Mek/Erk and PI3K/Akt signaling in MCF-10A cells (English)

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8 September 2017

Manish Tandon

1

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8 September 2017

Zujian Chen

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2

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8 September 2017

Jitesh Pratap

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3

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8 September 2017

language of work or name

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1 December 2014

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Journal of Cellular Biochemistry

8 September 2017

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8 September 2017

115

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8 September 2017

12

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8 September 2017

2208-2217

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Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance.

8 September 2017

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Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.

21 January 2018

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Runx2 in normal tissues and cancer cells: A developing story.

21 January 2018

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The RUNX family in breast cancer: relationships with estrogen signaling

21 January 2018

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Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development

21 January 2018

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G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression

21 January 2018

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Modelling glandular epithelial cancers in three-dimensional cultures

21 January 2018

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Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner

21 January 2018

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Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers

21 January 2018

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RUNX2 in mammary gland development and breast cancer.

21 January 2018

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EGFR signaling in breast cancer: bad to the bone.

21 January 2018

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Transcriptional regulation of osteoblasts.

21 January 2018

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MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation.

21 January 2018

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The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

21 January 2018

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Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells

21 January 2018

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Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development

21 January 2018

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Identification and functional characterization of ERK/MAPK phosphorylation sites in the Runx2 transcription factor.

21 January 2018

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Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells

21 January 2018

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ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells

21 January 2018

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Down-regulation of the PI3-kinase/Akt pathway by ERK MAP kinase in growth factor signaling.

21 January 2018

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The osteoblast transcription factor Runx2 is expressed in mammary epithelial cells and mediates osteopontin expression.

21 January 2018

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Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines

21 January 2018

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Cell signaling by receptor tyrosine kinases

21 January 2018

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ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling

21 January 2018

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Akt/protein kinase B activation by adenovirus vectors contributes to NFkappaB-dependent CXCL10 expression

21 January 2018

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CHIP regulates AKT/FoxO/Bim signaling in MCF7 and MCF10A cells

21 January 2018

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RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland

21 January 2018

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Potential involvement of Twist2 and Erk in the regulation of osteoblastogenesis by HB-EGF-EGFR signaling

21 January 2018

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Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells

21 January 2018

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Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression

21 January 2018

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Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation

21 January 2018

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

21 January 2018

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Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

21 January 2018

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Identification and characterization of Runx2 phosphorylation sites involved in matrix metalloproteinase-13 promoter activation

21 January 2018

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A role for Runx2 in normal mammary gland and breast cancer bone metastasis

21 January 2018

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The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability

21 January 2018

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Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells

21 January 2018

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EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF.

21 January 2018

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MEK inhibition leads to PI3K/AKT activation by relieving a negative feedback on ERBB receptors

21 January 2018

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FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

21 January 2018

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Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression

21 January 2018

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Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2.

21 January 2018

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Heparin-binding EGF-like growth factor and miR-1192 exert opposite effect on Runx2-induced osteogenic differentiation

21 January 2018

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EGFR signaling suppresses osteoblast differentiation and inhibits expression of master osteoblastic transcription factors Runx2 and Osterix.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCB.24939

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8 September 2017

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