Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). (Q48219972)

9 February 2018

title

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). (English)

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9 February 2018

familial hemophagocytic lymphohistiocytosis

main subject

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author

Véronique Minard-Colin

11

Véronique Minard-Colin

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Graça Raposo

3

Graça Raposo

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9 February 2018

Geneviève de Saint Basile

16

Geneviève de Saint Basile

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9 February 2018

Françoise Le Deist

14

Françoise Le Deist

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9 February 2018

Nathalie Lambert

7

Nathalie Lambert

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9 February 2018

author name string

Jérôme Feldmann

1

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9 February 2018

Isabelle Callebaut

2

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9 February 2018

Stéphanie Certain

4

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9 February 2018

Delphine Bacq

5

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9 February 2018

Cécile Dumont

6

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9 February 2018

Marie Ouachée-Chardin

8

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9 February 2018

Gaëlle Chedeville

9

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9 February 2018

Hannah Tamary

10

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9 February 2018

Véronique Minard-Colin

11

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9 February 2018

Etienne Vilmer

12

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9 February 2018

Stéphane Blanche

13

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9 February 2018

Alain Fischer

15

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9 February 2018

language of work or name

English

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publication date

1 November 2003

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9 February 2018

published in

Cell

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9 February 2018

volume

115

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9 February 2018

page(s)

461-473

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9 February 2018

issue

4

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9 February 2018

Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Regulation of transmitter release by Unc-13 and its homologues

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

The role of cytotoxicity in lymphocyte homeostasis.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Linkage of familial hemophagocytic lymphohistiocytosis to 10q21-22 and evidence for heterogeneity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

A conformational switch in syntaxin during exocytosis: role of munc18.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Fusion of cells by flipped SNAREs

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Membrane fusion and exocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

1 reference

7 January 2021

Protein secondary structure prediction based on position-specific scoring matrices

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Cell biology of cytotoxic and helper T cell functions: immunofluorescence microscopic studies of single cells and cell couples

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Mechanisms of synaptic vesicle exocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

The C2 domain calcium-binding motif: structural and functional diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Localization of a gene for familial hemophagocytic lymphohistiocytosis at chromosome 9q21.3-22 by homozygosity mapping

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Molecules relevant for T cell-target cell interaction are present in cytolytic granules of human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

C2-domains, structure and function of a universal Ca2+-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Snares and Munc18 in synaptic vesicle fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Lymphocyte-mediated cytotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Evaluation of comparative protein modeling by MODELLER

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Regulation of the UNC-18-Caenorhabditis elegans syntaxin complex by UNC-13

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

How do cytotoxic lymphocytes kill their targets?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

The immunological synapse of CTL contains a secretory domain and membrane bridges.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Structure of the Janus-faced C2B domain of rabphilin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Visualization of signaling pathways and cortical cytoskeleton in cytolytic and noncytolytic natural killer cell immune synapses.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

SNAREpins: minimal machinery for membrane fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

Rab proteins as membrane organizers

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900855-9

7 January 2021

10.1016/S0092-8674(03)00855-9

Identifiers

DOI

1 reference

9 February 2018

release_lfz4axhttnhn3bu7ixaw2nodk4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lfz4axhttnhn3bu7ixaw2nodk4

24 November 2022

mapped directly with Wikidata item

PubMed ID

14622600

1 reference

9 February 2018