Structure of the Janus-faced C2B domain of rabphilin (Q27620366)

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author name string

J Ubach

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J García

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M P Nittler

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J Rizo

The C2 domain calcium-binding motif: structural and functional diversity

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publication date

June 1999

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published in

Nature Cell Biology

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volume

1

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page(s)

106-12

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issue

2

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cites work

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C2-domains, structure and function of a universal Ca2+-binding domain

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Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold

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Crystal structure of a mammalian phosphoinositide-specific phospholipase C delta

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C2 domain conformational changes in phospholipase C-delta 1

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Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2

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Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A2

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Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+

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Crystal structure of the C2 domain from protein kinase C-delta

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Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C

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Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain?

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A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1

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Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?

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Synaptotagmin-syntaxin interaction: the C2 domain as a Ca2+-dependent electrostatic switch

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Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I

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Independent folding and ligand specificity of the C2 calcium-dependent lipid binding domain of cytosolic phospholipase A2

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Calcium-dependent membrane penetration is a hallmark of the C2 domain of cytosolic phospholipase A2 whereas the C2A domain of synaptotagmin binds membranes electrostatically.

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Synaptotagmins: C2-domain proteins that regulate membrane traffic

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Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin

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Doc2: a novel brain protein having two repeated C2-like domains

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Molecular cloning of an isoform of Doc2 having two C2-like domains

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Identification of a novel protein containing two C2 domains selectively expressed in the rat brain and kidney.

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Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse

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Distinct Ca(2+)-dependent properties of the first and second C2-domains of synaptotagmin I.

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A novel function for the second C2 domain of synaptotagmin. Ca2+-triggered dimerization.

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Synaptotagmin I is a high affinity receptor for clathrin AP-2: implications for membrane recycling

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A possible docking and fusion particle for synaptic transmission

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Interaction of the synprint site of N-type Ca2+ channels with the C2B domain of synaptotagmin I.

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Evidence that the Rab3a-binding protein, rabphilin3a, enhances regulated secretion. Studies in adrenal chromaffin cells

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The C2 domains of Rabphilin3A specifically bind phosphatidylinositol 4,5-bisphosphate containing vesicles in a Ca2+-dependent manner. In vitro characteristics and possible significance

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Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis

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Delineation of the oligomerization, AP-2 binding, and synprint binding region of the C2B domain of synaptotagmin

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Phosphorylation of rabphilin-3A by Ca2+/calmodulin- and cAMP-dependent protein kinases in vitro.

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Measurement of HN-H alpha J couplings in calcium-free calmodulin using new 2D and 3D water-flip-back methods

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