Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System. (Q47893021)

6 February 2018

review article

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title

Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System. (English)

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6 February 2018

author name string

Pei-Pei Liu

1

1 reference

6 February 2018

Ya-Jie Xu

2

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6 February 2018

Zhao-Qian Teng

3

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6 February 2018

Chang-Mei Liu

4

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6 February 2018

publication date

1 December 2017

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6 February 2018

published in

The Neuroscientist

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6 February 2018

page(s)

1073858417747839

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6 February 2018

BMI1 sustains human glioblastoma multiforme stem cell renewal

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The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease

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Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

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Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

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Polycomb Ezh2 controls the fate of GABAergic neurons in the embryonic cerebellum

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Histone methyltransferase enhancer of zeste homolog 2 regulates Schwann cell differentiation

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Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons

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Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition.

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21 January 2018

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21 January 2018

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21 January 2018

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Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms

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The Polycomb complex PRC2 and its mark in life

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21 January 2018

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21 January 2018

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Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

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The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation

21 January 2018

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Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

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Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes

21 January 2018

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The polycomb-group gene Ezh2 is required for early mouse development

21 January 2018

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Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons.

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The polycomb group protein Suz12 is required for embryonic stem cell differentiation

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JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

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Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

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Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

21 January 2018

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The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Epigenetic balance of gene expression by Polycomb and COMPASS families

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Polycomb controls gliogenesis by regulating the transient expression of the Gcm/Glide fate determinant

21 January 2018

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Coordinated regulation of dendrite arborization by epigenetic factors CDYL and EZH2.

21 January 2018

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The dynamics of polycomb group proteins in early embryonic nervous system in mouse and human

21 January 2018

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Immune function genes CD99L2, JARID2 and TPO show association with autism spectrum disorder

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Transcriptional Response of Polycomb Group Genes to Status Epilepticus in Mice is Modified by Prior Exposure to Epileptic Preconditioning.

21 January 2018

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The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Recruitment of Drosophila Polycomb-group proteins by Polycomblike, a component of a novel protein complex in larvae.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Ezh2 is required for neural crest-derived cartilage and bone formation.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Huntingtin facilitates polycomb repressive complex 2.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

21 January 2018

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Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes

21 January 2018

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Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

21 January 2018

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Dopamine signaling leads to loss of Polycomb repression and aberrant gene activation in experimental parkinsonism

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

The Arginine Methyltransferase PRMT6 Cooperates with Polycomb Proteins in Regulating HOXA Gene Expression

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Patterns of histone H3 lysine 27 monomethylation and erythroid cell type-specific gene expression

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Polycomb group protein ezh2 controls actin polymerization and cell signaling.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858417747839

The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Germline mutations in the oncogene EZH2 cause Weaver syndrome and increased human height.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Weaver syndrome and EZH2 mutations: Clarifying the clinical phenotype.

21 January 2018

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The development of neural stem cells

21 January 2018

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Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development

21 January 2018

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EZH2 mutation in an adolescent with Weaver syndrome developing acute myeloid leukemia and secondary hemophagocytic lymphohistiocytosis.

21 January 2018

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Profile of histone lysine methylation across transcribed mammalian chromatin

21 January 2018

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Role of PRC2-associated factors in stem cells and disease

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Decreased Methylation Level of H3K27me3 Increases Seizure Susceptibility.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

A new overgrowth syndrome with accelerated skeletal maturation, unusual facies, and camptodactyly

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Ezh2 regulates adult hippocampal neurogenesis and memory.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Ezh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

Erratum: Positional cloning of a global regulator of anterior–posterior patterning in mice

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858417747839

21 January 2018

Identifiers

DOI

10.1177/1073858417747839

1 reference

6 February 2018

PubMed ID

29283025

1 reference

6 February 2018