Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. (Q36386431)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26523864%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction (English)

1 reference

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28 February 2020

1 reference

2

1 reference

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28 February 2020

Joel Crespo

8

1 reference

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Sooryanarayana Varambally

28 February 2020

15

1 reference

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28 February 2020

3

Ilona Kryczek

1 reference

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28 February 2020

19

Jan Kotarski

1 reference

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28 February 2020

author name string

Ende Zhao

1

1 reference

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28 February 2020

Wei Li

4

1 reference

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28 February 2020

Ke Wu

5

1 reference

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28 February 2020

Lili Zhao

6

1 reference

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28 February 2020

Shuang Wei

7

1 reference

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28 February 2020

Shanshan Wan

9

1 reference

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28 February 2020

Linda Vatan

10

1 reference

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28 February 2020

Wojciech Szeliga

11

1 reference

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28 February 2020

Irene Shao

12

1 reference

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28 February 2020

Yin Wang

13

1 reference

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28 February 2020

Yan Liu

14

1 reference

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28 February 2020

Arul M Chinnaiyan

16

1 reference

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28 February 2020

Theodore H Welling

17

1 reference

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28 February 2020

Victor Marquez

18

1 reference

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28 February 2020

Hongbo Wang

20

1 reference

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28 February 2020

Zehua Wang

21

1 reference

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28 February 2020

Yi Zhang

22

1 reference

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28 February 2020

Rebecca Liu

23

1 reference

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28 February 2020

Guobin Wang

24

1 reference

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28 February 2020

Weiping Zou

25

1 reference

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28 February 2020

language of work or name

English

0 references

publication date

2 November 2015

1 reference

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28 February 2020

1 reference

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28 February 2020

volume

17

1 reference

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28 February 2020

issue

1

1 reference

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28 February 2020

page(s)

95-103

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IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L

28 February 2020

cites work

1 reference

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Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice

30 September 2017

1 reference

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T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming

30 September 2017

1 reference

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Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2.

30 September 2017

1 reference

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Posttranscriptional control of T cell effector function by aerobic glycolysis

30 September 2017

1 reference

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A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells

30 September 2017

1 reference

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T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment

30 September 2017

1 reference

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Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo

30 September 2017

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

30 September 2017

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Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells

30 September 2017

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Th17 cells are long lived and retain a stem cell-like molecular signature

30 September 2017

1 reference

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Human TH17 cells are long-lived effector memory cells.

30 September 2017

1 reference

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A human memory T cell subset with stem cell-like properties

30 September 2017

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30 September 2017

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Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells

30 September 2017

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T(H)17 cells in tumour immunity and immunotherapy.

30 September 2017

1 reference

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Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

30 September 2017

1 reference

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DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.

30 September 2017

1 reference

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Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

30 September 2017

1 reference

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Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

30 September 2017

1 reference

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Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

30 September 2017

1 reference

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Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

30 September 2017

1 reference

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MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

30 September 2017

1 reference

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Adoptive cell transfer: a clinical path to effective cancer immunotherapy

30 September 2017

1 reference

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An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses

30 September 2017

1 reference

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Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

30 September 2017

1 reference

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Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

30 September 2017

1 reference

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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

30 September 2017

1 reference

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

30 September 2017

1 reference

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B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

30 September 2017

1 reference

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Effector memory T cells, early metastasis, and survival in colorectal cancer

30 September 2017

1 reference

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The Polycomb group protein EZH2 directly controls DNA methylation

30 September 2017

1 reference

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Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

30 September 2017

1 reference

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Transition of late-stage effector T cells to CD27+ CD28+ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy

30 September 2017

1 reference

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

30 September 2017

1 reference

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Control of T cell viability

30 September 2017

1 reference

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Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

30 September 2017

1 reference

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Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

30 September 2017

1 reference

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The polycomb group protein EZH2 is involved in progression of prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

30 September 2017

1 reference

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Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

Time-dependent ROC curves for censored survival data and a diagnostic marker

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

Th17 cells have stem cell-like features and promote long-term immunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

The precursors of memory: models and controversies.

21 September 2018

1 reference

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Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684796

21 September 2018

Identifiers

DOI

10.1038/NI.3313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26523864%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26523864%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26523864%20AND%20SRC:MED&resulttype=core&format=json