Opportunities for organoids as new models of aging (Q47562383)

http://europepmc.org/abstract/PMC/5748992

7 July 2018

3 references

29 June 2019

19 September 2019

11 October 2019

Opportunities for organoids as new models of aging (English)

1 reference

http://europepmc.org/abstract/PMC/5748992

7 July 2018

main subject

biomedical investigative technique

1 reference

19 September 2019

1 reference

11 October 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Zev J Gartner

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Michael E Todhunter

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Mark A LaBarge

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

20 December 2017

1 reference

http://europepmc.org/abstract/PMC/5748992

7 July 2018

2 January 2018

3 references

29 June 2019

19 September 2019

11 October 2019

12

1 reference

inferred from page(s)

published in

Journal of Cell Biology

4 references

29 June 2019

19 September 2019

11 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

217

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

39-50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

An Organotypic 3D Assay for Primary Human Mammary Epithelial Cells that Recapitulates Branching Morphogenesis

31 May 2020

cites work

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Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion.

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Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

10 July 2018

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Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.

10 July 2018

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Dissecting the stem cell niche with organoid models: an engineering-based approach

10 July 2018

1 reference

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Lung organoids: current uses and future promise.

10 July 2018

1 reference

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Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

10 July 2018

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Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.

10 July 2018

1 reference

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Caloric restriction improves health and survival of rhesus monkeys

10 July 2018

1 reference

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Organoids: A historical perspective of thinking in three dimensions

10 July 2018

1 reference

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Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

10 July 2018

1 reference

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Tissue-specific mutation accumulation in human adult stem cells during life

10 July 2018

1 reference

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Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling

10 July 2018

1 reference

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Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes

10 July 2018

1 reference

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Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

10 July 2018

1 reference

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Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

10 July 2018

1 reference

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Three-dimensional bioprinting of thick vascularized tissues

10 July 2018

1 reference

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The Mechanobiology of Aging

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Back and forth in time: Directing age in iPSC-derived lineages.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Programmed synthesis of three-dimensional tissues.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Adaptive Immune Regulation of Mammary Postnatal Organogenesis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

The central role of muscle stem cells in regenerative failure with aging

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Mimicking the niche of lung epithelial stem cells and characterization of several effectors of their in vitro behavior.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

DNA methylation and healthy human aging

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation

10 July 2018

1 reference

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Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

In vitro generation of human pluripotent stem cell derived lung organoids

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Long-term culture of genome-stable bipotent stem cells from adult human liver

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

An in vivo model of human small intestine using pluripotent stem cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

A three-dimensional human neural cell culture model of Alzheimer's disease

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

3D culture assays of murine mammary branching morphogenesis and epithelial invasion

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Organoid cultures derived from patients with advanced prostate cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Identification of multipotent luminal progenitor cells in human prostate organoid cultures

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.

10 July 2018

1 reference

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Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation

10 July 2018

1 reference

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Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis

10 July 2018

1 reference

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You are what you host: microbiome modulation of the aging process

10 July 2018

1 reference

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Human iPSC-based modeling of late-onset disease via progerin-induced aging

10 July 2018

1 reference

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DNA methylation age of human tissues and cell types

10 July 2018

1 reference

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Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

10 July 2018

1 reference

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Young developmental age cardiac extracellular matrix promotes the expansion of neonatal cardiomyocytes in vitro

10 July 2018

1 reference

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Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load

10 July 2018

1 reference

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Type 2 alveolar cells are stem cells in adult lung.

10 July 2018

1 reference

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10 July 2018

The hallmarks of aging

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Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

The pivotal role of vascularization in tissue engineering

10 July 2018

1 reference

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Genomic responses in mouse models poorly mimic human inflammatory diseases

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration

10 July 2018

1 reference

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Long-lived cancer-resistant rodents as new model species for cancer research

10 July 2018

1 reference

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Genome-wide methylation profiles reveal quantitative views of human aging rates

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Multi-cell type human liver microtissues for hepatotoxicity testing

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Generation of functional thyroid from embryonic stem cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

The mouse as a model organism in aging research: usefulness, pitfalls and possibilities

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Controlled gene expression in primary Lgr5 organoid cultures

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Self-organizing optic-cup morphogenesis in three-dimensional culture

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Effects of aging on glomerular function and number in living kidney donors

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Neurogenic radial glia in the outer subventricular zone of human neocortex

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Lipofuscin: detection and quantification by microscopic techniques

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Matrix crosslinking forces tumor progression by enhancing integrin signaling

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Innate immune response to H3N2 and H1N1 influenza virus infection in a human lung organ culture model

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Inflammatory cytokine tumor necrosis factor alpha confers precancerous phenotype in an organoid model of normal human ovarian surface epithelial cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Engineered cardiac organoid chambers: toward a functional biological model ventricle

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

10 July 2018

Infection in the elderly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Evidence for a stem cell hierarchy in the adult human breast

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Immunosenescence: emerging challenges for an ageing population

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

An in vitro approach to the chronological aging of skin by glycation of the collagen: the biological effect of glycation on the reconstructed skin model

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Impaired RPE survival on aged submacular human Bruch's membrane

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Simple non-invasive assessment of advanced glycation endproduct accumulation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Oxygen accelerates the accumulation of mutations during the senescence and immortalization of murine cells in culture

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Experimental prostate epithelial morphogenesis in response to stroma and three-dimensional matrigel culture

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Advanced glycation end-products: a review

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Changes in circadian rhythms and sleep quality with aging: mechanisms and interventions

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Instability and decay of the primary structure of DNA

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Hormone regulation of human prostate in organ culture

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Epithelial-specific gene expression during differentiation of stratified primary human keratinocyte cultures

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Long-term Inflammation Transforms Intestinal Epithelial Cells of Colonic Organoids.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

A process engineering approach to increase organoid yield.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Retinoblastoma protein controls growth, survival and neuronal migration in human cerebral organoids.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Designer matrices for intestinal stem cell and organoid culture.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Generation of stomach tissue from mouse embryonic stem cells.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Using pancreas tissue slices for in situ studies of islet of Langerhans and acinar cell biology.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Genome sequencing of normal cells reveals developmental lineages and mutational processes

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Progesterone/RANKL is a major regulatory axis in the human breast.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Isolation of mammary-specific extracellular matrix to assess acute cell-ECM interactions in 3D culture.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

A new organotypic culture of thyroid tissue maintains three-dimensional follicles with C cells for a long term

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748992

A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201709054

Erratum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201709054

Increased production of tumor necrosis factor and interleukin-6 by arterial wall of aged rats

21 January 2018

1 reference

12 December 2020

A completely biological tissue-engineered human blood vessel

1 reference

12 December 2020

Long-term maintenance of mature hippocampal slices in vitro

1 reference

12 December 2020

The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis

1 reference

12 December 2020

Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice

1 reference

12 December 2020

Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach

1 reference

12 December 2020

Tissue-specific extracellular matrix coatings for the promotion of cell proliferation and maintenance of cell phenotype

1 reference

12 December 2020

Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels

1 reference

12 December 2020

An Improved Method of Renal Tissue Engineering, by Combining Renal Dissociation and Reaggregation with a Low-Volume Culture Technique, Results in Development of Engineered Kidneys Complete with Loops of Henle

1 reference

12 December 2020

In vitro 3-D model based on extending time of culture for studying chronological epidermis aging

1 reference

12 December 2020

An Air-Liquid Interface Culture System for 3D Organoid Culture of Diverse Primary Gastrointestinal Tissues

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.201709054

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263081%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference