Identification of multipotent luminal progenitor cells in human prostate organoid cultures (Q36635152)

15 August 2017

Identification of multipotent luminal progenitor cells in human prostate organoid cultures (English)

1 reference

15 August 2017

1 reference

9

Harry Begthel

1 reference

15 August 2017

Norman Sachs

10

0 references

Jarno Drost

object named as

Jarno Drost

3

0 references

Ruben van Boxtel

object named as

Ruben van Boxtel

5

0 references

Dong Gao

object named as

Dong Gao

8

0 references

author name string

Wouter R Karthaus

1

1 reference

15 August 2017

Phillip J Iaquinta

2

1 reference

15 August 2017

Ana Gracanin

4

1 reference

15 August 2017

John Wongvipat

6

1 reference

15 August 2017

Catherine M Dowling

7

1 reference

15 August 2017

Robert G J Vries

11

1 reference

15 August 2017

Edwin Cuppen

12

1 reference

15 August 2017

Yu Chen

13

1 reference

15 August 2017

Charles L Sawyers

14

1 reference

15 August 2017

Hans C Clevers

15

1 reference

15 August 2017

language of work or name

English

0 references

publication date

4 September 2014

1 reference

15 August 2017

1 reference

15 August 2017

159

1 reference

15 August 2017

163-175

1 reference

15 August 2017

1

1 reference

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Primary culture and propagation of human prostate epithelial cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

The mutational landscape of lethal castration-resistant prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Controlled gene expression in primary Lgr5 organoid cultures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

A framework for variation discovery and genotyping using next-generation DNA sequencing data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Molecular genetics of prostate cancer: new prospects for old challenges

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Integrative genomic profiling of human prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

A luminal epithelial stem cell that is a cell of origin for prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Fast and accurate short read alignment with Burrows-Wheeler transform

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Generation of a prostate from a single adult stem cell

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Noggin is required for normal lobe patterning and ductal budding in the mouse prostate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Self-renewal and multilineage differentiation in vitro from murine prostate stem cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Isolation and functional characterization of murine prostate stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Heterogeneity in primary and metastatic prostate cancer as defined by cell surface CD profile

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Hormonal, cellular, and molecular control of prostatic development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Roles for Nkx3.1 in prostate development and cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Pten is essential for embryonic development and tumour suppression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Multipotent and unipotent progenitors contribute to prostate postnatal development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Epithelial cell differentiation pathways in the human prostate: identification of intermediate phenotypes by keratin expression

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Identification of intermediate cell types by keratin expression in the developing human prostate

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Isolation and in vitro expansion of human colonic stem cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Prominin-1 (CD133) is not restricted to stem cells located in the basal compartment of murine and human prostate.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Permissive and instructive induction of adult rodent prostatic epithelium by heterotypic urogenital sinus mesenchyme.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772677

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201529

12 December 2020

inferred from PubMed ID database lookup

The role of androgens in the epithelio-mesenchymal interactions involved in prostatic morphogenesis in embryonic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201529

12 December 2020

inferred from PubMed ID database lookup

Instructive induction of prostate growth and differentiation by a defined urogenital sinus mesenchyme

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201529

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.CELL.2014.08.017

1 reference

release_wr3pz4ih2jgklc6vwwolddtx5u

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wr3pz4ih2jgklc6vwwolddtx5u

24 November 2022

mapped directly with Wikidata item

1 reference

15 August 2017

1 reference