Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors (Q34323334)

1 August 2017

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors (English)

1 reference

1 August 2017

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12

Lorenz Studer

1 reference

1 August 2017

11

Song-Hai Shi

1 reference

1 August 2017

Stuart M Chambers

1

1 reference

1 August 2017

Yuchen Qi

2

1 reference

1 August 2017

Yvonne Mica

3

1 reference

1 August 2017

Gabsang Lee

4

1 reference

1 August 2017

Xin-Jun Zhang

5

1 reference

1 August 2017

Lei Niu

6

1 reference

1 August 2017

James Bilsland

7

1 reference

1 August 2017

Lishuang Cao

8

1 reference

1 August 2017

Edward Stevens

9

1 reference

1 August 2017

Paul Whiting

10

1 reference

1 August 2017

language of work or name

1 reference

1 July 2012

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1 August 2017

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1 August 2017

30

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1 August 2017

7

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1 August 2017

715-720

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https://scigraph.springernature.com/pub.10.1038/nbt.2249

1 August 2017

0 references

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Pax6 is a human neuroectoderm cell fate determinant

6 July 2018

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Robust enhancement of neural differentiation from human ES and iPS cells regardless of their innate difference in differentiation propensity

6 July 2018

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Efficient derivation of functional floor plate tissue from human embryonic stem cells

6 July 2018

1 reference

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Technical challenges in using human induced pluripotent stem cells to model disease

6 July 2018

1 reference

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Differentiation of neural precursors and dopaminergic neurons from human embryonic stem cells

6 July 2018

1 reference

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Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

6 July 2018

1 reference

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

6 July 2018

1 reference

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BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage.

6 July 2018

1 reference

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BMP type I receptor inhibition reduces heterotopic [corrected] ossification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Nociceptors--noxious stimulus detectors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Hierarchical control of sensory neuron development by neurotrophic factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Specification and connectivity of neuronal subtypes in the sensory lineage.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Induction and specification of cranial placodes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Derivation of midbrain dopamine neurons from human embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

The P2X3 subunit: a molecular target in pain therapeutics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Regulation of Wnt signaling during adipogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Neurogenin1 and neurogenin2 control two distinct waves of neurogenesis in developing dorsal root ganglia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Control of neural crest cell fate by the Wnt signalling pathway.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

The capsaicin receptor: a heat-activated ion channel in the pain pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

The expression and posttranslational modification of a neuron-specific beta-tubulin isotype during chick embryogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Hepatocyte growth factor-Met signaling is required for Runx1 extinction and peptidergic differentiation in primary nociceptive neurons.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Runx1 selectively regulates cell fate specification and axonal projections of dorsal root ganglion neurons.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

The first neurons of the human cerebral cortex.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

A role for Runx transcription factor signaling in dorsal root ganglion sensory neuron diversification

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Sox10 regulates the development of neural crest-derived melanocytes in Xenopus.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Delta/Notch signaling promotes formation of zebrafish neural crest by repressing Neurogenin 1 function

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Development of neurogenic placodes in Xenopus laevis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516136

Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22750882

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neurogenesis of subpopulations of rat lumbar dorsal root ganglion neurons including neurons projecting to the dorsal column nuclei

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22750882

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nociceptive sensory neurons derive from contralaterally migrating, fate-restricted neural crest cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22750882

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NBT.2249

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference