Wild-type huntingtin participates in protein trafficking between the Golgi and the extracellular space (Q45303717)

11 December 2017

Wild-type huntingtin participates in protein trafficking between the Golgi and the extracellular space (English)

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11 December 2017

Anne N T Strehlow

1

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11 December 2017

Jun Z Li

series ordinal

2

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11 December 2017

Richard M Myers

series ordinal

3

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11 December 2017

language of work or name

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22 December 2006

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11 December 2017

Human Molecular Genetics

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11 December 2017

16

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11 December 2017

391-409

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11 December 2017

4

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Huntington's disease. Pathogenesis and management

11 December 2017

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https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Trinucleotide repeat length instability and age of onset in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Instability of CAG repeats in Huntington's disease: relation to parental transmission and age of onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntington's disease gene (IT15) is widely expressed in human and rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Widespread expression of Huntington's disease gene (IT15) protein product

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Inactivation of the mouse Huntington's disease gene homolog Hdh

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

The hunt for huntingtin function: interaction partners tell many different stories

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin-protein interactions and the pathogenesis of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin interacts with a family of WW domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Transcriptional abnormalities in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Normal huntingtin function: an alternative approach to Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Characterization and localization of the Huntington disease gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin localization in brains of normal and Huntington's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

YACs, BACs, PACs and MACs: artificial chromosomes as research tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

An efficient recombination system for chromosome engineering in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

A modular, positive selection bacterial artificial chromosome vector with multiple cloning sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Retrofitting BACs with G418 resistance, luciferase, and oriP and EBNA-1 - new vectors for in vitro and in vivo delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Life without huntingtin: normal differentiation into functional neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Secreted antagonists of the Wnt signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Functions of heparan sulfate proteoglycans in cell signaling during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Iron dysregulation and neurodegeneration: the molecular connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin contains a highly conserved nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

A huntingtin-associated protein enriched in brain with implications for pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Nervous system proteoglycans as modulators of neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Emerging roles for TGF-beta1 in nervous system development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

The role of matrix metalloproteinases in the morphogenesis of the cerebellar cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

A bacterial artificial chromosome library for sequencing the complete human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL467

21 January 2018

Identifiers

DOI

10.1093/HMG/DDL467

1 reference

release_vlq224shmrcrtov3tcd3ok7h34

11 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vlq224shmrcrtov3tcd3ok7h34

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference