Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo (Q24813199)

4 July 2017

Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo (English)

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4 July 2017

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GOA release 2020-03-11

6

Marcy E MacDonald

Marcy E

MacDonald

1 reference

4 July 2017

Juliana M Woda

1

Juliana M

Woda

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4 July 2017

Teresa Calzonetti

2

Teresa

Calzonetti

1 reference

4 July 2017

Paige Hilditch-Maguire

3

Paige

Hilditch-Maguire

1 reference

4 July 2017

Mabel P Duyao

4

Mabel P

Duyao

1 reference

4 July 2017

Ronald A Conlon

5

Ronald A

Conlon

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4 July 2017

language of work or name

English

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publication date

18 August 2005

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BMC Developmental Biology

4 July 2017

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4 July 2017

5

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4 July 2017

1

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page(s)

17

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https://scigraph.springernature.com/pub.10.1186/1471-213x-5-17

4 July 2017

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cites work

Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2

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The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor

7 April 2017

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Bmp4 is required for the generation of primordial germ cells in the mouse embryo

7 April 2017

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A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo

7 April 2017

1 reference

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

7 April 2017

2 references

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7 April 2017

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Huntingtin: alive and well and working in middle management

28 September 2017

1 reference

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The hunt for huntingtin function: interaction partners tell many different stories

7 April 2017

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Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

7 April 2017

1 reference

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Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

7 April 2017

1 reference

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Role of the anterior visceral endoderm in restricting posterior signals in the mouse embryo

7 April 2017

1 reference

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Neurological abnormalities in a knock-in mouse model of Huntington's disease

7 April 2017

1 reference

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Goosecoid and HNF-3beta genetically interact to regulate neural tube patterning during mouse embryogenesis

7 April 2017

1 reference

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Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation

7 April 2017

1 reference

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The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins

7 April 2017

1 reference

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Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Inactivation of the mouse Huntington's disease gene homolog Hdh

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Life without huntingtin: normal differentiation into functional neurons

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

HNF-3 beta is essential for node and notochord formation in mouse development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Expression pattern of the mouse T gene and its role in mesoderm formation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Bone morphogenetic protein 4 in the extraembryonic mesoderm is required for allantois development and the localization and survival of primordial germ cells in the mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Nodal signalling in vertebrate development.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Huntingtin is required for normal hematopoiesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Relationship between asymmetric nodal expression and the direction of embryonic turning

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Gastrulation in the mouse: the role of the homeobox gene goosecoid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

HEAT repeats in the Huntington's disease protein

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Analysis of mouse Evx genes: Evx-1 displays graded expression in the primitive streak

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Neural induction and patterning in the mouse in the absence of the node and its derivatives.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Huntingtin: a single bait hooks many species

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Anterior patterning in mouse.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Nodal signaling and axis formation in the mouse.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208873

Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo

28 November 2018

1 reference

12 December 2020

Imprinted X inactivation maintained by a mouse Polycomb group gene

1 reference

12 December 2020

Isolation and culture of whole postimplantation embryos and germ layer derivatives

1 reference

12 December 2020

Detection of messenger RNA by in situ hybridization to postimplantation embryo whole mounts

1 reference

12 December 2020

The eed mutation disrupts anterior mesoderm production in mice

1 reference

12 December 2020

Cell and tissue requirements for the gene eed during mouse gastrulation and organogenesis

1 reference

12 December 2020

Huntingtin: Alive and Well and Working in Middle Management

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-213X-5-17

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Dimensions Publication ID

4 July 2017

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1 reference

4 July 2017

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