The toxicity of SCH 351591, a novel phosphodiesterase-4 inhibitor, in Cynomolgus monkeys (Q44760134)

6 December 2017

The toxicity of SCH 351591, a novel phosphodiesterase-4 inhibitor, in Cynomolgus monkeys (English)

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6 December 2017

1 reference

ChEBI release 2020-05-28

Patricia E Losco

1

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6 December 2017

Ellen W Evans

2

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6 December 2017

Stephen A Barat

3

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6 December 2017

Pamela E Blackshear

4

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6 December 2017

Larisa Reyderman

5

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6 December 2017

Jay S Fine

6

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6 December 2017

Loretta A Bober

7

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6 December 2017

John C Anthes

8

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6 December 2017

Elmer J Mirro

9

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6 December 2017

Francis M Cuss

10

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6 December 2017

language of work or name

English

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publication date

1 May 2004

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6 December 2017

Toxicologic Pathology

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6 December 2017

32

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6 December 2017

3

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6 December 2017

295-308

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Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase 4 inhibitor.

6 December 2017

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Animal models of vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Chemical-induced vasculature injury. Summary of the symposium presented at the 32nd annual meeting of the Society of Toxicology, New Orleans, Louisiana, March 1993.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Differentiating spontaneous from drug-induced vascular injury in the dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Investigation into the role of phosphodiesterase IV in bronchorelaxation, including studies with human bronchus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Cardiotoxicity of vasodilators and positive inotropic/vasodilating drugs in dogs: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Cyclic nucleotide phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Effects of nonselective and isozyme selective cyclic nucleotide phosphodiesterase inhibitors on antigen-induced cytokine gene expression in peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Phosphodiesterase profile of human B lymphocytes from normal and atopic donors and the effects of PDE inhibition on B cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Phosphodiesterase 4 inhibitors and the treatment of asthma: where are we now and where do we go from here?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Characterization of the arteritis induced by infusion of rats with UK-61,260, an inodilator, for 24 h. A comparison with the arteritis induced by fenoldopam mesylate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Cardiotoxicity of a new inotrope/vasodilator drug (SK&F 94120) in the dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Emetic, central nervous system, and pulmonary activities of rolipram in the dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Mechanism for the emetic side effect of xanthine bronchodilators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

The next generation of PDE4 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Mesenteric arteriopathy in the rat induced by phosphodiesterase III inhibitors: an investigation of morphological, ultrastructural, and hemodynamic changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Pathogenesis of cardiovascular alterations in dogs treated with minoxidil

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Toxicologic and carcinogenic effects of the type IV phosphodiesterase inhibitor RP 73401 on the nasal olfactory tissue in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

PDE4 inhibitors induce emesis in ferrets via a noradrenergic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Multiple high-affinity cAMP-phosphodiesterases in human T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Influence of selective phosphodiesterase inhibitors on human neutrophil functions and levels of cAMP and Cai.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Apoptosis and Nitrative Stress Associated with Phosphodiesterase Inhibitor-Induced Mesenteric Vasculitis in Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Inhibition of neutrophil response by curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Phosphodiesterase isozymes: molecular targets for novel antiasthma agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Characteristic behavioral alterations in rats induced by rolipram and other selective adenosine cyclic 3?,5?-monophosphate phosphodiesterase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

SK&F 95654-induced acute cardiovascular toxicity in Sprague-Dawley rats--histopathologic, electron microscopic, and immunohistochemical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230490431493

10.1080/01926230490431493

21 January 2018

Identifiers

DOI

1 reference

6 December 2017

1 reference