Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons (Q44559480)

4 December 2017

Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons (English)

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4 December 2017

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C G Besirli

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4 December 2017

T L Deckwerth

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4 December 2017

R J Crowder

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4 December 2017

R S Freeman

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4 December 2017

E M Johnson

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4 December 2017

1 September 2003

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Cell Death & Differentiation

4 December 2017

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4 December 2017

10

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4 December 2017

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4 December 2017

1045-1058

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401259

4 December 2017

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

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Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

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Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

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Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

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Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation

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Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

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In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

21 January 2018

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Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

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Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons

21 January 2018

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Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation

21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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21 January 2018

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Analysis of the effects of the antiserum to the nerve growth factor in adult mice

21 January 2018

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Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

21 January 2018

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Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells

21 January 2018

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Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants

21 January 2018

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Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta

21 January 2018

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

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Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

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21 January 2018

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21 January 2018

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Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis).

21 January 2018

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Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

21 January 2018

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Cytosine arabinoside kills postmitotic neurons: evidence that deoxycytidine may have a role in neuronal survival that is independent of DNA synthesis

21 January 2018

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7 January 2021

Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction

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7 January 2021

A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside.

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7 January 2021

Cytosine arabinoside induces apoptosis in cerebellar neurons in culture.

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7 January 2021

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

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7 January 2021

Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53

1 reference

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7 January 2021

p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons

1 reference

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7 January 2021

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

1 reference

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7 January 2021

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

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7 January 2021

Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

1 reference

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7 January 2021

Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

p53 protein in sympathetic neurons: cytoplasmic localization and no apparent function in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Techniques in the tissue culture of rat sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401259

1 reference

4 December 2017

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