Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited (Q43067258)

13 November 2017

Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited (English)

1 reference

13 November 2017

3

Yves Pommier

1 reference

13 November 2017

Jing Tang

1

1 reference

13 November 2017

Kasthuraiah Maddali

series ordinal

2

1 reference

13 November 2017

Yuk Y Sham

series ordinal

4

1 reference

13 November 2017

Zhengqiang Wang

series ordinal

5

1 reference

13 November 2017

language of work or name

English

0 references

publication date

21 April 2010

1 reference

Bioorganic & Medicinal Chemistry Letters

13 November 2017

1 reference

13 November 2017

20

1 reference

13 November 2017

11

1 reference

13 November 2017

3275-3279

1 reference

Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase

13 November 2017

1 reference

12 December 2020

A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series

1 reference

12 December 2020

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

1 reference

12 December 2020

Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions

1 reference

12 December 2020

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

1 reference

12 December 2020

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

1 reference

12 December 2020

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

1 reference

12 December 2020

HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors.

1 reference

12 December 2020

Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors

1 reference

12 December 2020

HIV-1 integration: an interplay between HIV-1 integrase, cellular and viral proteins

1 reference

12 December 2020

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

1 reference

12 December 2020

Dynamic pharmacophore model optimization: identification of novel HIV-1 integrase inhibitors.

1 reference

12 December 2020

Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors

1 reference

12 December 2020

Molecular mechanisms in retrovirus DNA integration

1 reference

12 December 2020

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

1 reference

12 December 2020

Raltegravir: the first HIV integrase inhibitor

1 reference

12 December 2020

Developing a dynamic pharmacophore model for HIV-1 integrase.

1 reference

12 December 2020

HIV-1 IN inhibitors: 2010 update and perspectives

1 reference

12 December 2020

Seeing is believing: structure of the catalytic domain of HIV-1 integrase in complex with human LEDGF/p75.

1 reference

12 December 2020

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

1 reference

12 December 2020

Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection

1 reference

12 December 2020

Dihydroxypyrimidine-4-carboxamides as novel potent and selective HIV integrase inhibitors

1 reference

12 December 2020

Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.

1 reference

12 December 2020

Synthesis and antiviral activity of 7-benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV integrase inhibitors

1 reference

12 December 2020

Integrase inhibitors to treat HIV/AIDS.

1 reference

12 December 2020

Novel HIV-1 integrase inhibitors derived from quinolone antibiotics

1 reference

12 December 2020

Retroviral intasome assembly and inhibition of DNA strand transfer

1 reference

12 December 2020

Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

1 reference

12 December 2020

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

1 reference

12 December 2020

Strand transfer inhibitors of HIV-1 integrase: bringing IN a new era of antiretroviral therapy

1 reference

12 December 2020

Quinolone 3-carboxylic acid pharmacophore: design of second generation HIV-1 integrase inhibitors

1 reference

12 December 2020

Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs

1 reference

12 December 2020

Modeling, analysis, and validation of a novel HIV integrase structure provide insights into the binding modes of potent integrase inhibitors

1 reference

12 December 2020

The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral

1 reference

12 December 2020

Dynamic receptor-based pharmacophore model development and its application in designing novel HIV-1 integrase inhibitors

1 reference

12 December 2020

HIV reservoirs, latency, and reactivation: prospects for eradication

1 reference

12 December 2020

10.1016/J.BMCL.2010.04.048

Identifiers

DOI

1 reference

13 November 2017

1 reference