Seeing is believing: structure of the catalytic domain of HIV-1 integrase in complex with human LEDGF/p75. (Q34202103)

31 July 2017

Seeing is believing: structure of the catalytic domain of HIV-1 integrase in complex with human LEDGF/p75. (English)

1 reference

31 July 2017

Christina Marchetti Bradley

series ordinal

1

1 reference

PubMed ID

16314581

31 July 2017

Robert Craigie

series ordinal

2

1 reference

PubMed ID

16314581

31 July 2017

language of work or name

English

0 references

publication date

28 November 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

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31 July 2017

102

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31 July 2017

49

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31 July 2017

17543-17544

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Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Genome-wide analyses of avian sarcoma virus integration sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Human cell proteins and human immunodeficiency virus DNA integration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Transcription start regions in the human genome are favored targets for MLV integration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

HIV-1 integration in the human genome favors active genes and local hotspots

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Intracellular trafficking of retroviral genomes during the early phase of infection: viral exploitation of cellular pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Nuclear import of human immunodeficiency virus type-1 preintegration complexes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1308931

Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0509078102

Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0509078102

Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0509078102

21 January 2018

Identifiers

DOI

10.1073/PNAS.0509078102

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

16314581