p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes (Q42801936)

7 November 2017

p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes (English)

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7 November 2017

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7 November 2017

Ramón García-Escudero

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7 November 2017

A Besson

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Anna Bigas Salvans

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A Bigas

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author name string

L Espinosa

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7 November 2017

G Gundem

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7 November 2017

A Dominguez

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7 November 2017

S Orlando

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7 November 2017

E Gallastegui

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7 November 2017

C Saiz

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M J Pujol

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J M Paramio

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7 November 2017

O Bachs

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7 November 2017

language of work or name

English

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publication date

19 December 2011

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7 November 2017

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7 November 2017

31

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7 November 2017

4207-4220

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7 November 2017

38

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https://scigraph.springernature.com/pub.10.1038/onc.2011.582

7 November 2017

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Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression

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p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

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Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype

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Switching cyclin D-Cdk4 kinase activity on and off.

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Transcription factor map alignment of promoter regions

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Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis

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Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance

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Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer

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p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

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The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy

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Shared role of the pRB-related p130 and p107 proteins in limb development

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

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Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

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Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases

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IntOGen: integration and data mining of multidimensional oncogenomic data

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Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals

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Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family

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Kinesin motor proteins as targets for cancer therapy

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Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity

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Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles.

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

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Cell cycle kinases as therapeutic targets for cancer

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Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation

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Rb family proteins as modulators of gene expression and new aspects regarding the interaction with chromatin remodeling enzymes

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Mammalian cyclin-dependent kinases

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Cell cycle kinases in cancer

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Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

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p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

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p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex

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Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

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Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets

21 January 2018

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Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers

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Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

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p27Kip1 and p130 cooperate to regulate hematopoietic cell proliferation in vivo.

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Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.

21 January 2018

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

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31 March 2020

Identifiers

DOI

10.1038/ONC.2011.582

1 reference

Dimensions Publication ID

7 November 2017

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1 reference