p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells. (Q40450924)

20 September 2017

p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells. (English)

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20 September 2017

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Juan C Acosta

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Javier León

object named as

Javier León

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author name string

María J Muñoz-Alonso

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20 September 2017

Carlos Richard

3

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20 September 2017

M Dolores Delgado

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20 September 2017

John Sedivy

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20 September 2017

language of work or name

English

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publication date

3 March 2005

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

18

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20 September 2017

18120-18129

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CDK inhibitors: positive and negative regulators of G1-phase progression

20 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M500758200

Regulation of cyclin-Cdk activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500758200

New functional activities for the p21 family of CDK inhibitors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500758200

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Activation of cyclin D1-kinase in murine fibroblasts lacking both p21(Cip1) and p27(Kip1).

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500758200

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Cip/Kip proteins: more than just CDKs inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Cell cycle regulators and hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HL-60).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Evidence of a functional role for the cyclin-dependent kinase inhibitor p21(WAF1/CIP1/MDA6) in the reciprocal regulation of PKC activator-induced apoptosis and differentation in human myelomonocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Evidence of a functional role for the cyclin-dependent kinase inhibitor p21CIP1 in leukemic cell (U937) differentiation induced by low concentrations of 1-beta-D-arabinofuranosylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Max and inhibitory c-Myc mutants induce erythroid differentiation and resistance to apoptosis in human myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Molecular and transcriptional regulation of megakaryocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Reprogramming leukemic cells to terminal differentiation by inhibiting specific cyclin-dependent kinases in G1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Inducible p27(Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

p16(INK4a) induces differentiation and apoptosis in erythroid lineage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

The Protein SET Regulates the Inhibitory Effect of p21Cip1on Cyclin E-Cyclin-dependent Kinase 2 Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500758200

21 January 2018

Identifiers

DOI

10.1074/JBC.M500758200

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20 September 2017

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