Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease (Q42465415)

1 November 2017

Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease (English)

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1 November 2017

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1

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15 May 2020

author name string

Maryse Paquet

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632544&resulttype=core&format=json

15 May 2020

Lucimar T Ferreira

3

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15 May 2020

Tamara Cregan

4

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15 May 2020

Patrick Swan

5

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15 May 2020

Sean P Cregan

6

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15 May 2020

Stephen S G Ferguson

7

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15 May 2020

language of work or name

English

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publication date

1 January 2010

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1 November 2017

Journal of Neuroscience

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15 May 2020

volume

30

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15 May 2020

page(s)

316-324

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15 May 2020

issue

1

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Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems.

15 May 2020

cites work

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12 December 2020

Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin

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12 December 2020

Metabotropic glutamate receptors and cell-type-specific vulnerability in the striatum: implication for ischemia and Huntington's disease

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12 December 2020

Extracellular-signal-regulated kinase signalling in neurons

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12 December 2020

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

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12 December 2020

Cellular survival: a play in three Akts

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12 December 2020

Mutant huntingtin enhances excitotoxic cell death.

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12 December 2020

Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95.

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12 December 2020

An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors

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12 December 2020

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

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12 December 2020

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

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12 December 2020

The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt.

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12 December 2020

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

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12 December 2020

Phosphorylation-independent regulation of metabotropic glutamate receptor signaling by G protein-coupled receptor kinase 2.

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12 December 2020

Huntingtin in health and disease

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12 December 2020

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

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12 December 2020

Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells

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12 December 2020

PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

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12 December 2020

Huntingtin-protein interactions and the pathogenesis of Huntington's disease

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12 December 2020

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

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12 December 2020

Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

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12 December 2020

The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease

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12 December 2020

Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.

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12 December 2020

The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons

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12 December 2020

Phosphorylation-independent regulation of metabotropic glutamate receptor 1 signaling requires g protein-coupled receptor kinase 2 binding to the second intracellular loop

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12 December 2020

NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin

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12 December 2020

Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis

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12 December 2020

Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin

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12 December 2020

Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis

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12 December 2020

Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain

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12 December 2020

Desensitization of metabotropic glutamate receptors in neuronal cultures.

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12 December 2020

Excitotoxic injury of the neostriatum: a model for Huntington's disease

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12 December 2020

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease

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12 December 2020

Regulated recycling and plasma membrane recruitment of the high-affinity choline transporter

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12 December 2020

Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation

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12 December 2020

Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments

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12 December 2020

Phosphorylation-independent regulation of metabotropic glutamate receptor 5 desensitization and internalization by G protein-coupled receptor kinase 2 in neurons

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12 December 2020

Neuropathological classification of Huntington's disease

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12 December 2020

A new generation of Ca2+ indicators with greatly improved fluorescence properties

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12 December 2020

The metabotropic glutamate receptors: structure and functions

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12 December 2020

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

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12 December 2020

Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity.

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12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

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12 December 2020

Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

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12 December 2020

Pharmacology and functions of metabotropic glutamate receptors

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12 December 2020

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

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12 December 2020

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12 December 2020

Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse

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12 December 2020

10.1523/JNEUROSCI.4974-09.2010

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632544&resulttype=core&format=json

15 May 2020

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15 May 2020

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