Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin (Q40958511)

25 September 2017

Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin (English)

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25 September 2017

6

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25 September 2017

N Chen

1

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25 September 2017

T Luo

2

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25 September 2017

C Wellington

3

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25 September 2017

M Metzler

4

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25 September 2017

K McCutcheon

5

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25 September 2017

L A Raymond

7

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25 September 2017

language of work or name

English

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publication date

1 May 1999

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Journal of Neurochemistry

25 September 2017

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25 September 2017

72

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25 September 2017

1890-1898

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25 September 2017

5

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Alternative excitotoxic hypotheses

25 September 2017

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Ischemia-induced neuronal apoptosis

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Oxidative stress, glutamate, and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Survival of basal ganglia neuropeptide Y-somatostatin neurones in Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Excitotoxic injury of the neostriatum: a model for Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Inactivation of the mouse Huntington's disease gene homolog Hdh

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Synaptic targeting of glutamate receptors

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Selective sparing of a class of striatal neurons in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Cloned glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Evidence for silent synapses: implications for the expression of LTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

High probability opening of NMDA receptor channels by L-glutamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Aggregation of N-terminal huntingtin is dependent on the length of its glutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Huntington's disease gene (IT15) is widely expressed in human and rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

A huntingtin-associated protein enriched in brain with implications for pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Molecular mechanisms of glutamate receptor clustering at excitatory synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Glutamate receptor ion channel properties predict vulnerability to cytotoxicity in a transfected nonneuronal cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

The messenger RNAs for the N-methyl-D-aspartate receptor subunits show region-specific expression of different subunit composition in the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Calcium-induced actin depolymerization reduces NMDA channel activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

The tetrameric structure of a glutamate receptor channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

The quinolinic acid model of Huntington's disease: locomotor abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Widespread expression of Huntington's disease gene (IT15) protein product

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Competitive binding of alpha-actinin and calmodulin to the NMDA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

NMDA receptor losses in putamen from patients with Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

MOP2(SLA2) Affects the Abundance of the Plasma Membrane H+-ATPase ofSaccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

Rundown of N-methyl-D-aspartate channels during whole-cell recording in rat hippocampal neurons: role of Ca2+ and ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0721890.X

10.1046/J.1471-4159.1999.0721890.X

21 January 2018

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DOI

1 reference

25 September 2017

1 reference