BRCT domain interactions with phospho-histone H2A target Crb2 to chromatin at double-strand breaks and maintain the DNA damage checkpoint (Q42413619)

30 October 2017

BRCT domain interactions with phospho-histone H2A target Crb2 to chromatin at double-strand breaks and maintain the DNA damage checkpoint (English)

1 reference

phosphorylated histone binding

30 October 2017

0 references

1 reference

Gene Ontology release 2020-05-02

Oliver Limbo

3

0 references

Li-Lin Du

object named as

Li-Lin Du

2

0 references

author name string

Sevil Sofueva

1

1 reference

30 October 2017

Jessica S Williams

4

1 reference

30 October 2017

Paul Russell

5

1 reference

30 October 2017

language of work or name

English

0 references

publication date

2 August 2010

1 reference

Molecular and Cellular Biology

30 October 2017

1 reference

30 October 2017

30

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30 October 2017

19

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30 October 2017

4732-4743

1 reference

describes a project that uses

30 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2950532/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Requirement for the Phospho-H2AX Binding Module of Crb2 in Double-Strand Break Targeting and Checkpoint Activation

1 reference

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γH2A binds Brc1 to maintain genome integrity during S-phase

28 May 2018

1 reference

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Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping

28 May 2018

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Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

28 May 2018

1 reference

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53BP1: function and mechanisms of focal recruitment

28 May 2018

1 reference

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Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair

28 May 2018

1 reference

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Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast

28 May 2018

1 reference

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Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

28 May 2018

1 reference

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Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling

28 May 2018

1 reference

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Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks.

28 May 2018

1 reference

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Tudor, MBT and chromo domains gauge the degree of lysine methylation

28 May 2018

1 reference

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

28 May 2018

1 reference

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The role of double-strand break repair — insights from human genetics

28 May 2018

1 reference

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Cooperative control of Crb2 by ATM family and Cdc2 kinases is essential for the DNA damage checkpoint in fission yeast

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites

28 May 2018

1 reference

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Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair

28 May 2018

1 reference

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INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

28 May 2018

1 reference

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Sensing, signaling, and responding to DNA damage: organization of the checkpoint pathways in mammalian cells

28 May 2018

1 reference

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Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

28 May 2018

1 reference

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Cell-cycle checkpoints and cancer

28 May 2018

1 reference

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The DNA damage response: sensing and signaling

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and Rad3 complexes.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Mechanism of caffeine-induced checkpoint override in fission yeast

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Analysis of radiation-sensitive mutants of fission yeast

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Efficient targeted integration at leu1-32 and ura4-294 in Schizosaccharomyces pombe.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Molecular biology: DNA endgames.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950532

Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20679485

12 December 2020

inferred from PubMed ID database lookup

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20679485

12 December 2020

inferred from PubMed ID database lookup

Cdc2 Phosphorylation of Crb2 Is Required for Reestablishing Cell Cycle Progression after the Damage Checkpoint

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20679485

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/MCB.00413-10

1 reference

release_v6nxecf6yjctzokwmts547j3ay

30 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/v6nxecf6yjctzokwmts547j3ay

24 November 2022

mapped directly with Wikidata item

1 reference

30 October 2017

PubMed publication ID

20679485

1 reference