c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells. (Q42174623)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16507773%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells (English)

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17 January 2020

4

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17 January 2020

6

Arndt Borkhardt

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17 January 2020

author name string

Jay L Hess

1

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17 January 2020

Claudia B Bittner

2

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17 January 2020

Deniz T Zeisig

3

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17 January 2020

Uta Fuchs

5

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17 January 2020

Jon Frampton

7

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17 January 2020

Robert K Slany

8

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17 January 2020

language of work or name

English

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publication date

28 February 2006

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17 January 2020

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17 January 2020

volume

108

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17 January 2020

issue

1

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17 January 2020

page(s)

297-304

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MLL associates specifically with a subset of transcriptionally active target genes

17 January 2020

cites work

1 reference

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NUP98 fusion in human leukemia: dysregulation of the nuclear pore and homeodomain proteins

26 October 2017

1 reference

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Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

26 October 2017

1 reference

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Hox genes: from leukemia to hematopoietic stem cell expansion.

26 October 2017

1 reference

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Neuroblastoma targeting by c-myb-selective antisense oligonucleotides entrapped in anti-GD2 immunoliposome: immune cell-mediated anti-tumor activities.

26 October 2017

1 reference

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MEIS homeobox genes in neuroblastoma

26 October 2017

1 reference

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Hox regulation of normal and leukemic hematopoietic stem cells.

26 October 2017

1 reference

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Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus

26 October 2017

1 reference

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A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias

26 October 2017

1 reference

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Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells

26 October 2017

1 reference

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Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

26 October 2017

1 reference

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Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia

26 October 2017

1 reference

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Two distinct gene expression signatures in pediatric acute lymphoblastic leukemia with MLL rearrangements.

26 October 2017

1 reference

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Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Molecular characterization of acute leukemias by use of microarray technology

26 October 2017

1 reference

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Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

MEIS1 and HOXA7 genes in human acute myeloid leukemia

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

26 October 2017

1 reference

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Reassessing the role of C-MYB in tumorigenesis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus

26 October 2017

1 reference

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Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

26 October 2017

1 reference

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Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells

26 October 2017

1 reference

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Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation

26 October 2017

1 reference

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A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

26 October 2017

1 reference

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CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

The transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic cells

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895838

Quantitative HOX expression in chromosomally defined subsets of acute myelogenous leukemia

17 August 2018

1 reference

12 December 2020

Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny

1 reference

12 December 2020

Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation

1 reference

12 December 2020

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

1 reference

12 December 2020

Expression of B-myb in neuroblastoma tumors is a poor prognostic factor independent from MYCN amplification

1 reference

12 December 2020

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

1 reference

12 December 2020

10.1182/BLOOD-2005-12-5014

Identifiers

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17 January 2020

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