Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia (Q28273406)

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M P Lee

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L A Johnson

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K Ohyashiki

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K Toyama

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S J Chen

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C L Willman

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I M Chen

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A P Feinberg

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N A Jenkins

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N G Copeland

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J D Shaughnessy

https://scigraph.springernature.com/pub.10.1038/ng0296-154

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language of work or name

English

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publication date

February 1996

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published in

Nature Genetics

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volume

12

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page(s)

154-8

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issue

2

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exact match

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How proteins enter the nucleus

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The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA

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Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene

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Two additional cases of acute myeloid leukemia with t(7;11)(p15;p15) having low neutrophil alkaline phosphatase scores

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An integrated physical map of 210 markers assigned to the short arm of human chromosome 11.

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HRAS1 and INS genes are relocated but not structurally altered as a result of the t(7;11) (p15;p15) in a clone from a patient with acute myeloid leukaemia (M4)

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Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

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The human HOX gene family

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The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

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Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from chromosome 11

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The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm

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Translocation (7;11)(p15;p15) in acute myeloid leukemia M2: association with trilineage myelodysplasia and giant dysplastic myeloid cells

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Three tumor-suppressor regions on chromosome 11p identified by high-resolution deletion mapping in human non-small-cell lung cancer

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The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

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extradenticle raises the DNA binding specificity of homeotic selector gene products

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A comprehensive set of sequence analysis programs for the VAX

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