Cyclosporine inhibition of calcineurin activity in human leukocytes in vivo is rapidly reversible (Q41301944)

29 September 2017

Cyclosporine inhibition of calcineurin activity in human leukocytes in vivo is rapidly reversible (English)

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29 September 2017

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5

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29 September 2017

Batiuk TD

1

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29 September 2017

Pazderka F

series ordinal

2

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29 September 2017

Enns J

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3

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29 September 2017

DeCastro L

series ordinal

4

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29 September 2017

language of work or name

English

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publication date

1 September 1995

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Journal of Clinical Investigation

29 September 2017

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29 September 2017

96

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29 September 2017

3

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29 September 2017

1254-1260

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The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Calcineurin acts in synergy with PMA to inactivate I kappa B/MAD3, an inhibitor of NF-kappa B.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Lymphokine gene expression in vivo is inhibited by cyclosporin A.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Retention of activity by selected anthracyclines in a multidrug resistant human large cell lung carcinoma line without P-glycoprotein hyperexpression

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Solution structure of cyclosporin A and a nonimmunosuppressive analog bound to fully deuterated cyclophilin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

The mechanism of action of cyclosporin A and FK506

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Reduced cyclosporin accumulation in multidrug-resistant cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Energy-dependent processes involved in reduced drug accumulation in multidrug-resistant human lung cancer cell lines without P-glycoprotein expression

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Expression of multidrug resistance gene (MDR-1) in human normal leukocytes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

Induction of Interleukin 2 Messenger RNA Inhibited by Cyclosporin A

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=185746

NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugs

2 December 2018

1 reference

12 December 2020

Structure-based design of a cyclophilin-calcineurin bridging ligand

1 reference

12 December 2020

Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A

1 reference

12 December 2020

Calcineurin activity is only partially inhibited in leukocytes of cyclosporine-treated patients

1 reference

12 December 2020

Gamma interferon synthesis by human thymocytes and T lymphocytes inhibited by cyclosporin A

1 reference

12 December 2020

1H NMR studies on bovine cyclophilin: preliminary structural characterization of this specific cyclosporin A binding protein

1 reference

12 December 2020

Abbott TDx monoclonal antibody assay evaluated for measuring cyclosporine in whole blood

1 reference

12 December 2020

Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeast

1 reference

12 December 2020

Elective cyclosporine withdrawal after renal transplantation. A meta-analysis

1 reference

12 December 2020

Tapering or discontinuing cyclosporine for financial reasons--a single-center experience

1 reference

12 December 2020

Solution structure of the cyclosporin A/cyclophilin complex by NMR

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI118159

1 reference

release_lr2gq6thdrfkbjlg6acs7mzi2e

29 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lr2gq6thdrfkbjlg6acs7mzi2e

24 November 2022

mapped directly with Wikidata item

1 reference

29 September 2017

PubMed publication ID

7657799

1 reference