X-ray structure of a decameric cyclophilin-cyclosporin crystal complex (Q57003736)

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12 October 2019

title

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex (English)

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12 October 2019

6

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12 October 2019

author name string

Pflügl G

1

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12 October 2019

Kallen J

2

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12 October 2019

Schirmer T

3

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12 October 2019

Jansonius JN

4

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12 October 2019

Zurini MG

5

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12 October 2019

publication date

1 January 1993

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12 October 2019

language of work or name

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12 October 2019

volume

361

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12 October 2019

issue

6407

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12 October 2019

page(s)

91-94

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Cyclophilin: a specific cytosolic binding protein for cyclosporin A

12 October 2019

cites work

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Cyclosporin A in patients receiving renal allografts from cadaver donors

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Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B

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Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence

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Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: One in the presence and one in the absence of CsA

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Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

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Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

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Cis-transisomerization is rate-determining in the reactivation of denatured human carbonic anhydrase II as evidenced by proline isomerase

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Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

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Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

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FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

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7 January 2021

The X-ray structure of a tetrapeptide bound to the active site of human cyclophilin A

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7 January 2021

Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolution

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7 January 2021

The NMR structure of cyclosporin A bound to cyclophilin in aqueous solution

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7 January 2021

NMR studies of [U-13C]cyclosporin A bound to cyclophilin: bound conformation and portions of cyclosporin involved in binding

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7 January 2021

Cyclosporin A-cyclophilin complex formation. A model based on X-ray and NMR data

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7 January 2021

Molecular modeling studies of the complex between cyclophilin and cyclosporin A

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7 January 2021

Crystallisation and preliminary X-ray diffraction studies of cyclophilin-tetrapeptide and cyclophilin-cyclosporin complexes

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7 January 2021

Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

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7 January 2021

Successive action of DnaK, DnaJ and GroEL along the pathway of chaperone-mediated protein folding

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7 January 2021

Rotation function studies of human C-reactive protein

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7 January 2021

A pentameric form of human serum amyloid P component. Crystallization, X-ray diffraction and neutron scattering studies

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7 January 2021

Refined structure of spinach glycolate oxidase at 2 A resolution

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Crystallographic R factor refinement by molecular dynamics

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7 January 2021