Phosphatidylinositol 3-kinase related kinases (Q41102950)

26 September 2017

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title

Phosphatidylinositol 3-kinase related kinases (English)

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26 September 2017

Abraham RT

1

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26 September 2017

1 June 1996

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Current Opinion in Immunology

26 September 2017

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26 September 2017

8

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26 September 2017

412-418

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26 September 2017

3

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Phosphatidyl-inositol 3-kinase: a key enzyme in diverse signalling processes

26 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Phospholipid signaling

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

When is a lipid kinase not a lipid kinase? When it is a protein kinase

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Isolation and characterization of the Schizosaccharomyces pombe rad3 gene, involved in the DNA damage and DNA synthesis checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

The rad3+ gene of Schizosaccharomyces pombe is involved in multiple checkpoint functions and in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Purification of an 86-70 kDa nuclear DNA-associated protein complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

On the mechanisms of ku protein binding to DNA

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Cancer predisposition of ataxia-telangiectasia heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Incidence of cancer in 161 families affected by ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Juxtaposition of the T-cell receptor alpha-chain locus (14q11) and a region (14q32) of potential importance in leukemogenesis by a 14;14 translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Molecular analysis of a t(14;14) translocation in leukemic T-cells of an ataxia telangiectasia patient

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Immunopharmacology of rapamycin

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

The Rapamycin and FKBP12 Target (RAFT) Displays Phosphatidylinositol 4-Kinase Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Control of p70 s6 kinase by kinase activity of FRAP in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980132-4

7 January 2021

10.1016/S0952-7915(96)80132-4

Identifiers

DOI

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26 September 2017

1 reference

PubMed ID

8793996