TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast (Q27937613)

Phosphatidylinositol kinase-related protein kinase TOR2 YKL203C

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

S B Helliwell

1

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P Wagner

2

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J Kunz

3

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M Deuter-Reinhard

4

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R Henriquez

5

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M N Hall

Molecular Biology of the Cell

6

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language of work or name

English

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publication date

January 1994

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published in

1 reference

1 December 2016

5

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page(s)

105-18

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issue

1

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cites work

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

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Purification and characterization of phosphoinositide 3-kinase from rat liver

20 March 2017

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FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae

20 March 2017

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New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

20 March 2017

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Getting started with yeast

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Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast

20 March 2017

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A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli

20 March 2017

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Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

20 March 2017

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

20 March 2017

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Purification and characterization of a phosphatidylinositol kinase from A431 cells

20 March 2017

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

20 March 2017

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PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

20 March 2017

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Studies on the phosphorylation of myelin basic protein by protein kinase C and adenosine 3':5'-monophosphate-dependent protein kinase

20 March 2017

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A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

20 March 2017

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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

20 March 2017

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

20 March 2017

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Oncogenes and signal transduction

20 March 2017

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Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

7 April 2017

1 reference

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Inositol phosphates and cell signalling

7 April 2017

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Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect

7 April 2017

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

7 April 2017

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The mechanism of action of cyclosporin A and FK506

7 April 2017

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9 May 2017

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Stimulation of calcium uptake in Saccharomyces cerevisiae by bovine protein kinase C alpha

29 September 2017

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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

29 September 2017

1 reference

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A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Cyclosporin A, FK506 and rapamycin: more than just immunosuppression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

A protein kinase antigenically related to pp60v-src possibly involved in yeast cell cycle control: positive in vivo regulation by sterol

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Dimers, leucine zippers and DNA-binding domains

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

29 September 2017

Phosphoinositide kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

A yeast cyclophilin gene essential for lactate metabolism at high temperature

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Immunophilin-sensitive protein phosphatase action in cell signaling pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Divergent regulation of phosphatidylinositol 3-kinase P85 alpha and P85 beta isoforms upon T cell activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Purification and characterization of phosphatidylinositol kinase from porcine liver microsomes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Phosphatidylinositol 3-phosphate is present in normal and transformed fibroblasts and is resistant to hydrolysis by bovine brain phospholipase C II.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Metabolic and structural evidence for the existence of a third species of polyphosphoinositide in cells: D-phosphatidyl-myo-inositol 3-phosphate

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Cell cycle control by Ca2+ in Saccharomyces cerevisiae

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Analysis of inositol metabolites produced by Saccharomyces cerevisiae in response to glucose stimulation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301013

Substrate specificity of protein kinase C. Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements

27 November 2018

1 reference

12 December 2020

CDC25-dependent induction of inositol 1,4,5-trisphosphate and diacylglycerol in Saccharomyces cerevisiae by nitrogen

1 reference

12 December 2020

Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeast

1 reference

12 December 2020

Phosphatidylinositol 4-kinase from Saccharomyces cerevisiae. Kinetic analysis using Triton X-100/phosphatidylinositol-mixed micelles

1 reference

12 December 2020

Purification and characterization of a phosphatidylinositol 4-kinase from bovine uteri

1 reference

12 December 2020

Purification, characterization, and kinetic analysis of a 55-kDa form of phosphatidylinositol 4-kinase from Saccharomyces cerevisiae

1 reference

12 December 2020

Essential role for phosphatidylinositol 4,5-bisphosphate in yeast cell proliferation

1 reference

12 December 2020

The identification and purification of a mammalian- like protein kinase C in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

DNA of Saccharomyces cerevisiae

1 reference

12 December 2020

Polyphosphoinositides produced by phosphatidylinositol 3-kinase are poor substrates for phospholipases C from rat liver and bovine brain

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.5.1.105

1 reference

2332411

2332411

1 reference

1 reference

1 reference