Mechanisms of carcinogenesis and the mutant mouse (Q41099828)

26 September 2017

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title

Mechanisms of carcinogenesis and the mutant mouse (English)

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26 September 2017

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Williams BO

1

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PubMed ID

8791481

26 September 2017

Jacks T

series ordinal

2

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26 September 2017

1 February 1996

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Current Opinion in Genetics & Development

26 September 2017

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26 September 2017

6

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26 September 2017

65-70

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26 September 2017

1

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p53 is required for radiation-induced apoptosis in mouse thymocytes

26 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Tumor spectrum analysis in p53-mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Familial polyposis: recent advances

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Mutations in the APC gene and their implications for protein structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Genetic background alters the spectrum of tumors that develop in p53-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

A subset of p53-deficient embryos exhibit exencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

High-frequency developmental abnormalities in p53-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

DNA methylation and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Role for DNA methylation in genomic imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Suppression of intestinal neoplasia by DNA hypomethylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

DNA tumor virus transforming proteins and the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

The molecular genetics of cellular oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Transgenic mice as probes into complex systems

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

YAC transgenics and the study of genetics and human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Inducible gene targeting in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Effects of an Rb mutation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Requirement for a functional Rb-1 gene in murine development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

WT-1 is required for early kidney development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

The genetics of Wilms' tumor--a case of disrupted development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

The neurofibromatosis type 1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Ras signaling and NF1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

DCC: linking tumor suppressor genes and altered cell surface interactions in cancer?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Inhibition of transcription elongation by the VHL tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2990012-X

7 January 2021

10.1016/S0959-437X(96)90012-X

Identifiers

DOI

1 reference

26 September 2017

1 reference

PubMed ID

8791481