HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension (Q40972077)

25 September 2017

HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension (English)

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25 September 2017

13

Steeve Provencher

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25 September 2017

Olivier Boucherat

1

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25 September 2017

Sophie Chabot

2

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25 September 2017

Roxane Paulin

3

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25 September 2017

Isabelle Trinh

4

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25 September 2017

Alice Bourgeois

5

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25 September 2017

François Potus

6

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25 September 2017

Marie-Claude Lampron

7

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25 September 2017

Caroline Lambert

8

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25 September 2017

Sandra Breuils-Bonnet

9

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25 September 2017

Valérie Nadeau

10

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25 September 2017

Renée Paradis

11

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25 September 2017

Elena A Goncharova

12

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25 September 2017

Sébastien Bonnet

14

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25 September 2017

language of work or name

English

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publication date

3 July 2017

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25 September 2017

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25 September 2017

7

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25 September 2017

4546

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25 September 2017

1

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Creative Commons Attribution 4.0 International

25 September 2017

start time

3 July 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/s41598-017-04874-4

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cites work

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DNA Damage and Pulmonary Hypertension

25 September 2017

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Metformin Reverses Development of Pulmonary Hypertension via Aromatase Inhibition

25 September 2017

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HDAC6 promotes cell proliferation and confers resistance to temozolomide in glioblastoma

25 September 2017

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Molecular Mechanisms of Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension

25 September 2017

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Combination therapy versus monotherapy for pulmonary arterial hypertension: a meta-analysis

25 September 2017

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Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases.

25 September 2017

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Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy

25 September 2017

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SMAR1 coordinates HDAC6-induced deacetylation of Ku70 and dictates cell fate upon irradiation

25 September 2017

1 reference

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Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

25 September 2017

1 reference

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HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling

25 September 2017

1 reference

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Antidepressant-like properties of novel HDAC6-selective inhibitors with improved brain bioavailability

25 September 2017

1 reference

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Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH.

25 September 2017

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Histone deacetylase 6 (HDAC6) deacetylates survivin for its nuclear export in breast cancer

25 September 2017

1 reference

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Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism

25 September 2017

1 reference

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A novel class of small molecule inhibitors of HDAC6.

25 September 2017

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Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension

25 September 2017

1 reference

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HDAC6 deacetylates Ku70 and regulates Ku70-Bax binding in neuroblastoma

25 September 2017

1 reference

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Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents

25 September 2017

1 reference

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Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension

25 September 2017

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Targeting the dynamic HSP90 complex in cancer

25 September 2017

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Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A

25 September 2017

1 reference

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Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer

25 September 2017

1 reference

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Inflammation, growth factors, and pulmonary vascular remodeling

25 September 2017

1 reference

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HIF-1alpha and STAT3 client proteins interacting with the cancer chaperone Hsp90: therapeutic considerations

25 September 2017

1 reference

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HDAC6 a new cellular stress surveillance factor.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

HDAC6 is a microtubule-associated deacetylase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Regulation of Pim-1 by Hsp90

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Histone deacetylase inhibition with trichostatin A does not reverse severe angioproliferative pulmonary hypertension in rats (2013 Grover Conference series).

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Bromodomain-Containing Protein 4: The Epigenetic Origin of Pulmonary Arterial Hypertension.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Translational Advances in the Field of Pulmonary Hypertension. From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics. Targeting Cell Growth and Proliferation Signaling Hubs.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Role for Runt-related Transcription Factor 2 in Proliferative and Calcified Vascular Lesions in Pulmonary Arterial Hypertension.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Role for DNA damage signaling in pulmonary arterial hypertension

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hypertension.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

HDAC6 promotes hepatocellular carcinoma progression by inhibiting P53 transcriptional activity

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5495763

miR-223 reverses experimental pulmonary arterial hypertension

19 August 2018

2 references

Crossref

https://api.crossref.org/works/10.1038%2FS41598-017-04874-4

7 January 2021

inferred from DOI database lookup

PubMed

https://pubmed.ncbi.nlm.nih.gov/28674407

12 December 2020

inferred from PubMed ID database lookup

HDAC6 Promotes Cardiac Fibrosis Progression through Suppressing RASSF1A Expression

2 references

Crossref

https://api.crossref.org/works/10.1038%2FS41598-017-04874-4

7 January 2021

inferred from DOI database lookup

PubMed

https://pubmed.ncbi.nlm.nih.gov/28674407

12 December 2020

inferred from PubMed ID database lookup

Loss of bone morphogenetic protein receptor 2 is associated with abnormal DNA repair in pulmonary arterial hypertension

2 references

Crossref

https://api.crossref.org/works/10.1038%2FS41598-017-04874-4

7 January 2021

inferred from DOI database lookup

PubMed

https://pubmed.ncbi.nlm.nih.gov/28674407

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41598-017-04874-4

1 reference

Dimensions Publication ID

25 September 2017

0 references

1 reference

25 September 2017

1 reference