HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates (Q28114913)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates (English)

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

main subject

cytotoxicity

0 references

Histone deacetylase 6

1 reference

misfolded protein binding

1 reference

Valosin containing protein

1 reference

Heat shock factor 1

1 reference

Histone deacetylase 6

1 reference

author

Saadi Khochbin

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Cyril Boyault

1

1 reference

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5 January 2020

Claire Vourc'H

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

author name string

Yu Zhang

2

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Sabrina Fritah

3

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Cécile Caron

4

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Benoit Gilquin

5

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

So Hee Kwon

6

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Carmen Garrido

7

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Tso-Pang Yao

8

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Patrick Matthias

10

2 references

3 January 2017

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5 January 2020

publication date

1 September 2007

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

21

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

page(s)

2172-2181

1 reference

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5 January 2020

issue

17

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes

5 January 2020

cites work

1 reference

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HDAC6 is a microtubule-associated deacetylase

20 March 2017

1 reference

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

20 March 2017

1 reference

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HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

20 March 2017

1 reference

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HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes

20 March 2017

1 reference

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Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

20 March 2017

1 reference

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Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2

20 March 2017

1 reference

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Doa1 is a Cdc48 adapter that possesses a novel ubiquitin binding domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

20 March 2017

1 reference

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Aggresomes: a cellular response to misfolded proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

HDAC6-p97/VCP controlled polyubiquitin chain turnover

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Aggresomes, inclusion bodies and protein aggregation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Protein degradation and protection against misfolded or damaged proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Proteasome inhibitors: valuable new tools for cell biologists

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Hsp90: a chaperone for protein folding and gene regulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Cdc48p is UBX-linked to ER ubiquitin ligases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Heat shock response modulators as therapeutic tools for diseases of protein conformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Class II histone deacetylases: from sequence to function, regulation, and clinical implication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

On mechanisms that control heat shock transcription factor activity in metazoan cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

From the cradle to the grave: molecular chaperones that may choose between folding and degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Stress-specific activation and repression of heat shock factors 1 and 2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Proteasome inhibitors MG132 and lactacystin hyperphosphorylate HSF1 and induce hsp70 and hsp27 expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Heat shock response and protein degradation: regulation of HSF2 by the ubiquitin-proteasome pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Evidence for the involvement of mouse heat shock factor 1 in the atypical expression of the HSP70.1 heat shock gene during mouse zygotic genome activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950856

Proteasome inhibition leads to the activation of all members of the heat-shock-factor family

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17785525

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p97, a protein coping with multiple identities

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17785525

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.436407

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17785525%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

2 references