A role for E2F1 in Ras activation of p21(WAF1/CIP1) transcription (Q40895969)

24 September 2017

title

A role for E2F1 in Ras activation of p21(WAF1/CIP1) transcription (English)

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24 September 2017

A L Gartel

1

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24 September 2017

F Najmabadi

series ordinal

2

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24 September 2017

E Goufman

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3

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24 September 2017

A L Tyner

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4

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24 September 2017

language of work or name

English

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publication date

1 February 2000

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24 September 2017

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24 September 2017

volume

19

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24 September 2017

issue

7

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24 September 2017

page(s)

961-964

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p21(WAF1/CIP1) is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: involvement of the small GTPase rhoA.

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Complementation of defective colony-stimulating factor 1 receptor signaling and mitogenesis by Raf and v-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Histone deacetylase 1 can repress transcription by binding to Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Inhibition of cyclin-dependent kinases by p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Oncogenic capacity of the E2F1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

A novel substrate for assays of gene expression using chloramphenicol acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Regulation of the cyclin E gene by transcription factor E2F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

A role for Rho in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Endogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Mechanism of active transcriptional repression by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Retinoblastoma protein switches the E2F site from positive to negative element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

p53 and E2F-1 cooperate to mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Multiple members of the E2F transcription factor family are the products of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

K-ras modulates the cell cycle via both positive and negative regulatory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

7 January 2021

Activation and repression of p21(WAF1/CIP1) transcription by RB binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

7 January 2021

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

7 January 2021

Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203411

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203411

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Dimensions Publication ID

24 September 2017

1004615600

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1 reference