PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway. (Q40738816)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

title

PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

author name string

Lucy C Coles

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

language of work or name

English

0 references

publication date

1 March 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

page(s)

2236-2244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205302

9 December 2019

exact match

0 references

cites work

A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Regulation of Raf-1 activation and signalling by dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Mechanism of inhibition of Raf-1 by protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Paradoxical activation of Raf by a novel Raf inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Reconstitution of mitogen-activated protein kinase phosphorylation cascades in bacteria. Efficient synthesis of active protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Mitogen-activated protein (MAP) kinase phosphorylation of MAP kinase kinase: determination of phosphorylation sites by mass spectrometry and site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Negative regulation of Raf-1 by phosphorylation of serine 621.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

The complexity of Raf-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Identification of residues in the cysteine-rich domain of Raf-1 that control Ras binding and Raf-1 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

inferred from DOI database lookup

7 January 2021

based on heuristic

Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1205302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 December 2019

0 references

1 reference