A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian Numb (Q40584703)

21 September 2017

A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian Numb (English)

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21 September 2017

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Jing Nie

1

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21 September 2017

Shawn S-C Li

series ordinal

2

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21 September 2017

C Jane McGlade

series ordinal

3

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21 September 2017

language of work or name

English

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publication date

27 February 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

20

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21 September 2017

20807-20815

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

21 September 2017

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Themes and variations on ubiquitylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Mechanisms underlying ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

The anaphase-promoting complex: new subunits and regulators

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Felix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Solution structure of a Nedd4 WW domain-ENaC peptide complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

The Lnx family proteins function as molecular scaffolds for Numb family proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Mesodermal cell fate decisions in Drosophila are under the control of the lineage genes numb, Notch, and sanpodo.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Asymmetric cell division in the Drosophila nervous system

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

The Mdm2 oncoprotein interacts with the cell fate regulator Numb

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

SAP couples Fyn to SLAM immune receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Coordination of an array of signaling proteins through homo- and heteromeric interactions between PDZ domains and target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

Formation of a native-like beta-hairpin finger structure of a peptide from the extended PDZ domain of neuronal nitric oxide synthase in aqueous solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

Peptide-surface association: the case of PDZ and PTB domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

MDM2 suppresses p73 function without promoting p73 degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311396200

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311396200

21 January 2018

Identifiers

DOI

10.1074/JBC.M311396200

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21 September 2017

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