Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb (Q27622039)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747019%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb (English)

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5 November 2019

1

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5 November 2019

Julie Forman-Kay

5

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5 November 2019

author name string

S C Li

2

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5 November 2019

L E Kay

3

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5 November 2019

T Pawson

4

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5 November 2019

language of work or name

English

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publication date

1 April 2000

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5 November 2019

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5 November 2019

volume

19

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5 November 2019

issue

7

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5 November 2019

page(s)

1505-1515

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FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

5 November 2019

cites work

1 reference

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Structural view of the Ran-Importin beta interaction at 2.3 A resolution

20 March 2017

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Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly

20 March 2017

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Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity

20 March 2017

1 reference

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The Mdm2 oncoprotein interacts with the cell fate regulator Numb

20 March 2017

1 reference

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Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain

20 March 2017

1 reference

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Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module

20 March 2017

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The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

20 March 2017

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Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain

20 March 2017

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Structure and ligand recognition of the phosphotyrosine binding domain of Shc

20 March 2017

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Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

20 March 2017

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NMR View: A computer program for the visualization and analysis of NMR data

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

20 March 2017

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MOLMOL: a program for display and analysis of macromolecular structures

20 March 2017

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

20 March 2017

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SH2 domains recognize specific phosphopeptide sequences

20 March 2017

1 reference

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Protein modules and signalling networks

20 March 2017

1 reference

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Signaling through scaffold, anchoring, and adaptor proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

20 March 2017

Asymmetric cell division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins

20 March 2017

1 reference

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Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization

29 September 2017

1 reference

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High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Affinity, specificity, and kinetics of the interaction of the SHC phosphotyrosine binding domain with asparagine-X-X-phosphotyrosine motifs of growth factor receptors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Asymmetric segregation of Numb and Prospero during cell division

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310220

Specificity of the PTB domain of Shc for beta turn-forming pentapeptide motifs amino-terminal to phosphotyrosine

27 November 2018

1 reference

PubMed

12 December 2020

Functional analysis of the Numb phosphotyrosine-binding domain using site-directed mutagenesis

1 reference

PubMed

12 December 2020

A phosphotyrosine interaction domain

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/19.7.1505

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747019%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747019%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

2 references