Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway (Q40572900)

21 September 2017

Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway (English)

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21 September 2017

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2

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21 September 2017

Daniel Shegogue

1

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PubMed ID

15047702

21 September 2017

language of work or name

English

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publication date

26 March 2004

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Journal of Biological Chemistry

21 September 2017

10

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based on heuristic

inferred from page(s)

published in

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21 September 2017

279

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21 September 2017

23166-23175

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21 September 2017

22

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The transforming growth factor-beta family

21 September 2017

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Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail

21 January 2018

1 reference

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Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins

21 January 2018

1 reference

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Role of protein kinase C-delta in the regulation of collagen gene expression in scleroderma fibroblasts

21 January 2018

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c-Jun-dependent inhibition of cutaneous procollagen transcription following ultraviolet irradiation is reversed by all-trans retinoic acid

21 January 2018

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UV irradiation activates JNK and increases alphaI(I) collagen gene expression in rat hepatic stellate cells

21 January 2018

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

21 January 2018

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Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

21 January 2018

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Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein

21 January 2018

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

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RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

21 January 2018

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TOR, a central controller of cell growth

21 January 2018

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TOR signalling and control of cell growth

21 January 2018

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The TOR signaling cascade regulates gene expression in response to nutrients

21 January 2018

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Control of p70 s6 kinase by kinase activity of FRAP in vivo

21 January 2018

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4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

21 January 2018

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Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation

21 January 2018

1 reference

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Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

21 January 2018

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Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3' untranslated region

21 January 2018

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The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae

21 January 2018

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Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis

21 January 2018

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Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase

21 January 2018

1 reference

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Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

21 January 2018

1 reference

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Attenuation of mammalian target of rapamycin activity by increased cAMP in 3T3-L1 adipocytes

21 January 2018

1 reference

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Regulation of translation initiation by FRAP/mTOR

21 January 2018

1 reference

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Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation

21 January 2018

1 reference

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Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

21 January 2018

1 reference

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Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts

21 January 2018

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Analysis of human interleukin-5 gene transcription by a novel nuclear run on method based on the polymerase chain reaction

21 January 2018

1 reference

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Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells

21 January 2018

1 reference

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Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes

21 January 2018

1 reference

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Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability

21 January 2018

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Regulation of type I collagen mRNA in lung fibroblasts by cystine availability

21 January 2018

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Messenger RNA deadenylylation precedes decapping in mammalian cells

21 January 2018

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A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase.

21 January 2018

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Mechanism of action of the immunosuppressant rapamycin

21 January 2018

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Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics

21 January 2018

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A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids

21 January 2018

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Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinase

21 January 2018

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Phosphatidic acid-mediated mitogenic activation of mTOR signaling

21 January 2018

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The Phosphatidylinositol 3-Kinase/Akt Pathway Enhances Smad3-stimulated Mesangial Cell Collagen I Expression in Response to Transforming Growth Factor-β1

21 January 2018

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Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

21 January 2018

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Downregulation of collagen synthesis in fibroblasts within three-dimensional collagen lattices involves transcriptional and posttranscriptional mechanisms.

21 January 2018

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

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Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon

21 January 2018

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Mechanism of TGFbeta receptor inhibition by FKBP12

21 January 2018

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Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

21 January 2018

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Sustained suppression of neointimal proliferation by sirolimus-eluting stents: one-year angiographic and intravascular ultrasound follow-up

21 January 2018

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Overcoming restenosis with sirolimus: from alphabet soup to clinical reality

21 January 2018

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Posttranscriptional regulation of collagen alpha1(I) mRNA in hepatic stellate cells

21 January 2018

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Differential regulation of transcription and transcript stability of pro-alpha 1(I) collagen and fibronectin in activated fibroblasts derived from patients with systemic scleroderma

21 January 2018

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FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M401238200

1 reference

21 September 2017

1 reference

PubMed ID

15047702