Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinase (Q24318156)

GOA release 2020-03-11

signal transduction

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

author name string

R Meyers

series ordinal

1

0 references

L C Cantley

series ordinal

2

0 references

language of work or name

English

0 references

publication date

14 February 1997

0 references

published in

0 references

volume

272

0 references

issue

7

0 references

page(s)

4384-90

0 references

cites work

A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Studies and perspectives of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Phosphatidylinositol 4,5-bisphosphate synthesis is required for activation of phospholipase D in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Bovine brain contains two types of phosphatidylinositol kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

A monoclonal antibody distinguishes two types of phosphatidylinositol 4-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Cloning, expression, and localization of 230-kDa phosphatidylinositol 4-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

The scanning model for translation: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Purification and characterization of human erythrocyte phosphatidylinositol 4-kinase. Phosphatidylinositol 4-kinase and phosphatidylinositol 3-monophosphate 4-kinase are distinct enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384

inferred from DOI database lookup

7 January 2021

based on heuristic

Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.7.4384