Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death. (Q40526299)

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31 December 2019

title

Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death (English)

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31 December 2019

3

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author name string

C A Colton

1

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31 December 2019

Q Xu

2

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31 December 2019

S Y Bae

4

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31 December 2019

J K Wakefield

5

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31 December 2019

A Nair

6

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31 December 2019

W J Strittmatter

7

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31 December 2019

M P Vitek

8

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31 December 2019

language of work or name

English

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publication date

1 August 2004

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31 December 2019

published in

Journal of Neuroscience

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31 December 2019

volume

24

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31 December 2019

issue

32

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31 December 2019

page(s)

7118-7127

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Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue

31 December 2019

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Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels.

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Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening

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Striatal nitric oxide signaling regulates the neuronal activity of midbrain dopamine neurons in vivo

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Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos

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Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells

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Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea

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Arginase I: a limiting factor for nitric oxide and polyamine synthesis by activated macrophages?

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Voltage-dependent ion channels in CAD cells: A catecholaminergic neuronal line that exhibits inducible differentiation

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Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells

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Mutant huntingtin enhances excitotoxic cell death.

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Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications

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The selective vulnerability of nerve cells in Huntington's disease

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Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders

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Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport

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Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation

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Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N(1)-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice

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Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

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Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease

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Amino Acid Sequence Requirements of Peptides That Inhibit Polyglutamine-Protein Aggregation and Cell Death

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Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: effects of L-NAME on symptom progression

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Expression of arginase isozymes in mouse brain

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NMDA receptor function in mouse models of Huntington disease

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Effects of arginase isoforms on NO Production by nNOS

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

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Altered neuronal nitric oxide synthase expression contributes to disease progression in Huntington's disease transgenic mice

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Local circuit neurons in the striatum regulate neural and behavioral responses to dopaminergic stimulation

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Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development

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Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

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12 December 2020

Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro.

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12 December 2020

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

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12 December 2020

GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity.

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12 December 2020

Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders

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12 December 2020

Cellular polyamines promote the aggregation of alpha-synuclein

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12 December 2020

An activity-dependent spermine-mediated mechanism that modulates glutamate transmission

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Polycation-induced oligomerization and accelerated fibrillation of human alpha-synuclein in vitro

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Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system.

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A perspective of polyamine metabolism

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Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington disease

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Nitric oxide production and regulation of neuronal NOS in tyrosine hydroxylase containing neurons

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Characterization of a transgenic mouse line over-expressing the human ornithine decarboxylase gene

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12 December 2020

The quinolinic acid hypothesis in Huntington's chorea

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12 December 2020

Combined regulation of ornithine and S-adenosylmethionine decarboxylases by spermine and the spermine analogue N1 N12-bis(ethyl)spermine

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Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors

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Determination of arginase activity in macrophages: a micromethod

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Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits.

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Regulation of spermidine/spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis

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Differential post-transcriptional control of ornithine decarboxylase and spermidine-spermine N1-acetyltransferase by polyamines

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Comparative properties of arginases

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Activation of polyamine catabolism profoundly alters tissue polyamine pools and affects hair growth and female fertility in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.

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10.1523/JNEUROSCI.1233-04.2004

Identifiers

DOI

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31 December 2019

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31 December 2019

PubMed publication ID

15306645

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