Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders (Q34952853)

5 August 2017

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title

Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders (English)

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5 August 2017

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Christopher A Ross

1

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PubMed ID

12372277

5 August 2017

language of work or name

English

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publication date

1 August 2002

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5 August 2017

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5 August 2017

35

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5 August 2017

819-822

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5 August 2017

5

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Impairment of the ubiquitin-proteasome system by protein aggregation

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Loss of normal huntingtin function: new developments in Huntington's disease research

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Mutant protein in Huntington disease is resistant to proteolysis in affected brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Expansion explosion: new clues to the pathogenesis of repeat expansion neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

CREB-binding protein sequestration by expanded polyglutamine

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Molecular pathogenesis of spinal and bulbar muscular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Beyond the Qs in the polyglutamine diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Nuclear targeting of mutant Huntingtin increases toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

When more is less: pathogenesis of glutamine repeat neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Lessons from animal models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Toxic proteins in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Huntington's disease: the challenge for cell biologists

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Comparison of huntingtin proteolytic fragments in human lymphoblast cell lines and human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900872-3

7 January 2021

10.1016/S0896-6273(02)00872-3

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12372277