Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators. (Q40163126)

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English	Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.	scientific article

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Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators (English)

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Jill H Fowler

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Fumarate modulates the immune/inflammatory response and rescues nerve cells and neurological function after stroke in rats

1 reference

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Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice

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MCP-1-mediated activation of microglia promotes white matter lesions and cognitive deficits by chronic cerebral hypoperfusion in mice.

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Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion

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14 September 2018

Dimethyl Fumarate Ameliorates Lewis Rat Experimental Autoimmune Neuritis and Mediates Axonal Protection

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Preconditioning with VEGF Enhances Angiogenic and Neuroprotective Effects of Bone Marrow Mononuclear Cell Transplantation in a Rat Model of Chronic Cerebral Hypoperfusion

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Glutathione Deficit Affects the Integrity and Function of the Fimbria/Fornix and Anterior Commissure in Mice: Relevance for Schizophrenia

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T cell immunity to glatiramer acetate ameliorates cognitive deficits induced by chronic cerebral hypoperfusion by modulating the microenvironment

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Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage

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Dimethyl Fumarate Protects Brain From Damage Produced by Intracerebral Hemorrhage by Mechanism Involving Nrf2.

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Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS.

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Fructus mume alleviates chronic cerebral hypoperfusion-induced white matter and hippocampal damage via inhibition of inflammation and downregulation of TLR4 and p38 MAPK signaling

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Ecto-5'-nucleotidase (CD73) is involved in chronic cerebral hypoperfusion-induced white matter lesions and cognitive impairment by regulating glial cell activation and pro-inflammatory cytokines.

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Dimethyl fumarate attenuates cerebral edema formation by protecting the blood-brain barrier integrity.

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HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis.

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Sitagliptin attenuated brain damage and cognitive impairment in mice with chronic cerebral hypo-perfusion through suppressing oxidative stress and inflammatory reaction.

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A comparative analysis of multiple sclerosis-relevant anti-inflammatory properties of ethyl pyruvate and dimethyl fumarate.

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Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease

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Dimethylfumarate alleviates early brain injury and secondary cognitive deficits after experimental subarachnoid hemorrhage via activation of Keap1-Nrf2-ARE system.

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L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain

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Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion

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Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice

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Neonatal hyperoxia exposure disrupts axon-oligodendrocyte integrity in the subcortical white matter

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N-methyl-D-aspartate receptor-mediated axonal injury in adult rat corpus callosum

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14 September 2018

WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination

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14 September 2018

Roles of white matter in central nervous system pathophysiologies

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Rapid disruption of axon-glial integrity in response to mild cerebral hypoperfusion

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Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

1 reference

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14 September 2018

Selective white matter pathology induces a specific impairment in spatial working memory.

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14 September 2018

Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammation

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14 September 2018

Functional recovery of callosal axons following demyelination: a critical window

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14 September 2018

Assaying the functional effects of demyelination and remyelination: revisiting field potential recordings.

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14 September 2018

Oligodendrocytes: facilitating axonal conduction by more than myelination

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14 September 2018

Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice

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14 September 2018

White matter vulnerability to ischemic injury increases with age because of enhanced excitotoxicity.

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Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice

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Preferential neuroprotective effect of tacrolimus (FK506) on unmyelinated axons following traumatic brain injury

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14 September 2018

White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury.

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14 September 2018

Electrophysiological changes in isolated spinal cord white matter in response to oxygen deprivation

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14 September 2018

Minocycline attenuates white matter damage in a rat model of chronic cerebral hypoperfusion

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14 September 2018

Myelinated and unmyelinated axons of the corpus callosum differ in vulnerability and functional recovery following traumatic brain injury

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Cerebral small-vessel disease and decline in information processing speed, executive function and memory.

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Upregulation of oligodendrocyte progenitor cells associated with restoration of mature oligodendrocytes and myelination in peri-infarct area in the rat brain

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Molecular mechanisms of axonal damage in inflammatory central nervous system diseases

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Periventricular cerebral white matter lesions predict rate of cognitive decline

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14 September 2018

Blood-brain barrier disruption in white matter lesions in a rat model of chronic cerebral hypoperfusion

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14 September 2018

Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain.

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14 September 2018

Ampa/kainate receptor activation mediates hypoxic oligodendrocyte death and axonal injury in cerebral white matter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

Changes in axonal physiology and morphology after chronic compressive injury of the rat thoracic spinal cord

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

Differential production of MCP-1 and cytokine-induced neutrophil chemoattractant in the ischemic brain after transient focal ischemia in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

Selective glial vulnerability following transient global ischemia in rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

Nitric oxide donors reversibly block axonal conduction: demyelinated axons are especially susceptible.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

Induction of macrophage inflammatory protein MIP-1alpha mRNA on glial cells after focal cerebral ischemia in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

Cerebral white matter is highly vulnerable to ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

14 September 2018

MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice

1 reference

https://api.crossref.org/works/10.1177%2F0271678X17713105

21 January 2018

CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke

1 reference

https://api.crossref.org/works/10.1177%2F0271678X17713105

21 January 2018

A Role for Interferon-Gamma in Focal Cerebral Ischemia in Mice

2 references

https://api.crossref.org/works/10.1177%2F0271678X17713105

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6077928

2 December 2018

Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration

1 reference

https://pubmed.ncbi.nlm.nih.gov/28606007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/28606007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1177/0271678X17713105

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28606007%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28606007%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28606007%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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