YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (Q40112218)

17 September 2017

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (English)

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17 September 2017

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5

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17 September 2017

4

Jon Goguen

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17 September 2017

3

Douglas T Golenbock

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17 September 2017

Charles R Sweet

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PubMed ID

17608743

17 September 2017

Joseph Conlon

series ordinal

2

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17 September 2017

30 June 2007

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17 September 2017

Cellular Microbiology

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17 September 2017

9

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17 September 2017

11

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17 September 2017

2700-2715

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A FADD-dependent innate immune mechanism in mammalian cells

17 September 2017

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https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

TRAF6 is a signal transducer for interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Signal-induced Ubiquitination of IκB Kinase-β

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The type III secretion injectisome

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia enterocolitica YopP-induced apoptosis of macrophages involves the apoptotic signaling cascade upstream of bid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

MAP kinases in the immune response

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia outer protein P suppresses TGF-beta-activated kinase-1 activity to impair innate immune signaling in Yersinia enterocolitica-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Type I interferon signaling is required for activation of the inflammasome during Francisella infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

5'-Triphosphate RNA is the ligand for RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Innate immune recognition

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Antiviral signaling through pattern recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The plague virulence protein YopM targets the innate immune response by causing a global depletion of NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Plague bacteria target immune cells during infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The bacterial protein YopJ abrogates multiple signal transduction pathways that converge on the transcription factor CREB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

pEF-BOS, a powerful mammalian expression vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Type I interferon production enhances susceptibility to Listeria monocytogenes infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Function of the Yersinia effector YopJ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

MEROPS: the peptidase database.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia outer protein P of Yersinia enterocolitica simultaneously blocks the nuclear factor-kappa B pathway and exploits lipopolysaccharide signaling to trigger apoptosis in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The yopJ locus is required for Yersinia-mediated inhibition of NF-kappaB activation and cytokine expression: YopJ contains a eukaryotic SH2-like domain that is essential for its repressive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

TLR3 in antiviral immunity: key player or bystander?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Antiviral innate immunity pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

NF-kappaB signaling pathways in mammalian and insect innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Interference of eukaryotic signalling pathways by the bacteria Yersinia outer protein YopJ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

IRF family of transcription factors as regulators of host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Contribution of the major secreted yops of Yersinia enterocolitica O:8 to pathogenicity in the mouse infection model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia outer protein P inhibits CD8 T cell priming in the mouse infection model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

VISA is an adapter protein required for virus-triggered IFN-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia effector YopJ inhibits yeast MAPK signaling pathways by an evolutionarily conserved mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Role of Toll-like receptor signaling in the apoptotic response of macrophages to Yersinia infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00990.X

10.1111/J.1462-5822.2007.00990.X

21 January 2018

Identifiers

DOI

1 reference

17 September 2017

1 reference

PubMed ID

17608743