B-Raf(V600E) signaling deregulates the mitotic spindle checkpoint through stabilizing Mps1 levels in melanoma cells (Q40037013)

16 September 2017

B-Raf(V600E) signaling deregulates the mitotic spindle checkpoint through stabilizing Mps1 levels in melanoma cells (English)

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16 September 2017

Cui Y

1

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16 September 2017

Guadagno TM

series ordinal

2

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16 September 2017

language of work or name

English

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publication date

10 December 2007

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16 September 2017

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16 September 2017

27

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16 September 2017

22

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16 September 2017

3122-3133

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210972

16 September 2017

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cites work

Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.

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The spindle checkpoint, aneuploidy, and cancer

21 January 2018

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B-Raf is critical for MAPK activation during mitosis and is regulated in an M phase-dependent manner in Xenopus egg extracts.

21 January 2018

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MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation

21 January 2018

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Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

21 January 2018

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Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells

21 January 2018

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Distinct sets of genetic alterations in melanoma

21 January 2018

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Mutations of the BRAF gene in human cancer

21 January 2018

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Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint

21 January 2018

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The mouse Mps1p-like kinase regulates centrosome duplication

21 January 2018

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BRAF mutations in papillary carcinomas of the thyroid

21 January 2018

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Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption.

21 January 2018

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A requirement for MAP kinase in the assembly and maintenance of the mitotic spindle

21 January 2018

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Chromosome segregation and cancer: cutting through the mystery

21 January 2018

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Cdc28/Cdk1 regulates spindle pole body duplication through phosphorylation of Spc42 and Mps1.

21 January 2018

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B-RAF is a therapeutic target in melanoma

21 January 2018

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Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints

21 January 2018

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On the road to cancer: aneuploidy and the mitotic checkpoint

21 January 2018

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Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores

21 January 2018

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The MAP kinase pathway is required for entry into mitosis and cell survival.

21 January 2018

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Segregating sister genomes: the molecular biology of chromosome separation

21 January 2018

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RKIP downregulates B-Raf kinase activity in melanoma cancer cells

21 January 2018

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A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence

21 January 2018

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The anaphase-promoting complex: proteolysis in mitosis and beyond

21 January 2018

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Deregulated Akt3 activity promotes development of malignant melanoma

21 January 2018

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Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication

21 January 2018

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MAP kinase is required for the spindle assembly checkpoint but is dispensable for the normal M phase entry and exit in Xenopus egg cell cycle extracts

21 January 2018

1 reference

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A role for mitogen-activated protein kinase in the spindle assembly checkpoint in XTC cells

21 January 2018

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V599EB-RAF is an oncogene in melanocytes

21 January 2018

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Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210972

Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210972

Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210972

7 January 2021

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210972

7 January 2021

Anaphase inactivation of the spindle checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210972

7 January 2021

Mps1 phosphorylation by MAP kinase is required for kinetochore localization of spindle-checkpoint proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210972

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210972

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Dimensions Publication ID

16 September 2017

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1 reference