ΔF508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments (Q39703906)

14 September 2017

ΔF508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments (English)

1 reference

14 September 2017

protein ubiquitination

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Rafal Bartoszewski

6

1 reference

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9 June 2020

author name string

Andras Rab

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Li ping Tang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Zsuzsa Bebok

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Steven M Rowe

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

James F Collawn

7

1 reference

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9 June 2020

language of work or name

English

0 references

publication date

16 April 2015

1 reference

14 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

10

1 reference

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9 June 2020

issue

4

1 reference

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9 June 2020

page(s)

e0123131

1 reference

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Creative Commons Attribution 4.0 International

9 June 2020

copyright license

start time

16 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Stabilizing rescued surface-localized δf508 CFTR by potentiation of its interaction with Na(+)/H(+) exchanger regulatory factor 1.

1 reference

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Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target

14 September 2017

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Dynamic exchange of myosin VI on endocytic structures

14 September 2017

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Nedd4-2 does not regulate wt-CFTR in human airway epithelial cells

14 September 2017

1 reference

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Signaling-mediated control of ubiquitin ligases in endocytosis.

14 September 2017

1 reference

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Disabled-2 protein facilitates assembly polypeptide-2-independent recruitment of cystic fibrosis transmembrane conductance regulator to endocytic vesicles in polarized human airway epithelial cells

14 September 2017

1 reference

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Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator

14 September 2017

1 reference

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Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.

14 September 2017

1 reference

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Benzbromarone stabilizes ΔF508 CFTR at the cell surface

14 September 2017

1 reference

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Targets for cystic fibrosis therapy: proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulator

14 September 2017

1 reference

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c-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cells

14 September 2017

1 reference

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Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine

14 September 2017

1 reference

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Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures

14 September 2017

1 reference

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Mechanisms for rescue of correctable folding defects in CFTRDelta F508.

14 September 2017

1 reference

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Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway

14 September 2017

1 reference

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Ubiquitin in trafficking: the network at work

14 September 2017

1 reference

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CFTR function and prospects for therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Evidence for airway surface dehydration as the initiating event in CF airway disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Advances in cystic fibrosis therapies

14 September 2017

1 reference

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Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Clathrin-mediated endocytosis in AP-2-depleted cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

A macromolecular complex of beta 2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Conformational and temperature-sensitive stability defects of the delta F508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Clathrin is a key regulator of basolateral polarity.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Peripheral protein quality control removes unfolded CFTR from the plasma membrane

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Enhanced cell-surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Corrector VX-809 stabilizes the first transmembrane domain of CFTR.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Search and rescue: finding ways to correct deltaF508 CFTR.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Mutations in the amino terminus of the cystic fibrosis transmembrane conductance regulator enhance endocytosis

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Mu 2 binding directs the cystic fibrosis transmembrane conductance regulator to the clathrin-mediated endocytic pathway

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

The carboxyl terminus of the cystic fibrosis transmembrane conductance regulator binds to AP-2 clathrin adaptors.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Analysis of the structural requirements for lysosomal membrane targeting using transferrin receptor chimeras

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4399842

Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25879443

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Endocytic adaptor complexes bind the C-terminal domain of CFTR

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25879443

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0123131

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879443%20AND%20SRC:MED&resulttype=core&format=json