An inactivating CYLD mutation promotes skin tumor progression by conferring enhanced proliferative, survival and angiogenic properties to epidermal cancer cells (Q39656299)

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scientific article published on 13 September 2010

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English	An inactivating CYLD mutation promotes skin tumor progression by conferring enhanced proliferative, survival and angiogenic properties to epidermal cancer cells	scientific article published on 13 September 2010

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scholarly article

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Europe PubMed Central

13 September 2017

An inactivating CYLD mutation promotes skin tumor progression by conferring enhanced proliferative, survival and angiogenic properties to epidermal cancer cells (English)

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Europe PubMed Central

13 September 2017

tumor progression

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based on heuristic

inferred from title

author name string

J P Alameda

1

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Europe PubMed Central

13 September 2017

R Moreno-Maldonado

2

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Europe PubMed Central

13 September 2017

M Navarro

3

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Europe PubMed Central

13 September 2017

A Bravo

4

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Europe PubMed Central

13 September 2017

A Ramírez

5

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Europe PubMed Central

13 September 2017

A Page

6

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Europe PubMed Central

13 September 2017

J L Jorcano

7

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Europe PubMed Central

13 September 2017

M J Fernández-Aceñero

8

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Europe PubMed Central

13 September 2017

M L Casanova

9

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Europe PubMed Central

13 September 2017

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publication date

13 September 2010

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Europe PubMed Central

13 September 2017

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Europe PubMed Central

13 September 2017

29

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Europe PubMed Central

13 September 2017

6522-6532

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Europe PubMed Central

13 September 2017

50

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13 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2010.378

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IKKalpha enhances human keratinocyte differentiation and determines the histological variant of epidermal squamous cell carcinomas

1 reference

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21 January 2018

Angiogenesis in mice with chronic airway inflammation: strain-dependent differences

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Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

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Identification of the familial cylindromatosis tumour-suppressor gene

1 reference

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Angiogenesis is an early event in the development of chemically induced skin tumors

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Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

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31 March 2020

Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis

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31 March 2020

Angiogenesis in health and disease

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31 March 2020

Epidermal abnormalities and increased malignancy of skin tumors in human epidermal keratin 8-expressing transgenic mice.

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31 March 2020

Wnt/beta-catenin signaling in development and disease

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Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

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Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays

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NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

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Carcinosarcoma arising in a patient with multiple cylindromas

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Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

1 reference

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31 March 2020

The role of VEGF and thrombospondins in skin angiogenesis

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31 March 2020

Tumor angiogenesis

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31 March 2020

Malignant transformation of multiple dermal cylindromas

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31 March 2020

A matter of life and cell death

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31 March 2020

VEGF: an update on biological and therapeutic aspects

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31 March 2020

VEGF and the quest for tumour angiogenesis factors

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The biology of VEGF and its receptors

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31 March 2020

5' flanking and first intron sequences of the human beta-actin gene required for efficient promoter activity

1 reference

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31 March 2020

A matter of life and death

1 reference

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31 March 2020

The Hallmarks of Cancer

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31 March 2020

Analysis of DNA copy number aberrations in hepatitis C virus-associated hepatocellular carcinomas by conventional CGH and array CGH.

1 reference

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31 March 2020

Reduced expression of CYLD in human colon and hepatocellular carcinomas

1 reference

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31 March 2020

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.378

31 March 2020

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

1 reference

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31 March 2020

Lessons from hereditary colorectal cancer

1 reference

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31 March 2020

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

1 reference

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31 March 2020

VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development.

1 reference

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31 March 2020

Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.378

31 March 2020

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.378

31 March 2020

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma

1 reference

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31 March 2020

Cylindromatosis and the CYLD gene: new lessons on the molecular principles of epithelial growth control.

1 reference

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31 March 2020

Complexity of VEGF responses in skin carcinogenesis revealed through ex vivo assays based on a VEGF-A null mouse keratinocyte cell line.

1 reference

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31 March 2020

WNT and beta-catenin signalling: diseases and therapies

1 reference

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31 March 2020

Ras gene mutation and amplification in human nonmelanoma skin cancers

1 reference

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31 March 2020

Wnts induce migration and invasion of myeloma plasma cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.378

31 March 2020

The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.378

31 March 2020

Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappaB signaling

1 reference

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31 March 2020

Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis

1 reference

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31 March 2020

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

1 reference

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31 March 2020

Activated ras genes occur in human actinic keratoses, premalignant precursors to squamous cell carcinomas

1 reference

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31 March 2020

Spiradenocylindroma of the kidney: clinical and genetic findings suggesting a role of somatic mutation of the CYLD1 gene in the oncogenesis of an unusual renal neoplasm

1 reference

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31 March 2020

Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.

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31 March 2020

Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl

1 reference

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31 March 2020

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

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Tissue-specific expression of murine keratin K13 in internal stratified squamous epithelia and its aberrant expression during two-stage mouse skin carcinogenesis is associated with the methylation state of a distinct CpG site in the remote 5'-flanki

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Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.

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31 March 2020

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10.1038/ONC.2010.378

1 reference

Europe PubMed Central

13 September 2017

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1 reference

Europe PubMed Central

13 September 2017

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